{"id":1882858,"date":"2026-04-14T05:00:43","date_gmt":"2026-04-14T02:00:43","guid":{"rendered":"https:\/\/analyse.optim.biz\/?p=1882858"},"modified":"2026-04-14T05:00:43","modified_gmt":"2026-04-14T02:00:43","slug":"ai-fails-at-primary-patient-diagnosis-more-than-80-of-the-time-study-finds","status":"publish","type":"post","link":"https:\/\/analyse.optim.biz\/?p=1882858","title":{"rendered":"AI fails at primary patient diagnosis more than 80% of the time, study finds"},"content":{"rendered":"<p>[analyse_image type=&#8221;featured&#8221; src=&#8221;https:\/\/images.euronews.com\/articles\/stories\/09\/72\/02\/63\/1200x675_cmsv2_27833b7a-bb6b-5ca1-bacf-fc8b2a496bf4-9720263.jpg&#8221;]<\/p>\n<article id=\"abe-2885218-pos1-c-latest-stories\" class=\"the-media-object m-modeMobile-1 m-modeDesktop-1 m-modeXL-1 the-media-object--has-video\" data-nid=\"2885218\" data-cid=\"9717516\" data-part-label=\"Partner content\">\n<figure id=\"abe-2885218-label-pos1-c-latest-stories\" 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width=\"16\"><\/figure>\n<div class=\"the-media-object__content\">\n                    Europe Today<\/p>\n<div class=\"the-media-object__title  \"><span class=\"c-article-title__prefix--red\">Live.<\/span><\/p>\n<p>    After historic Israel\u2013Lebanon talks, is a ceasefire within reach?\n  <\/p><\/div>\n<\/div>\n<\/article>\n<article id=\"abe-2885890-pos2-c-latest-stories-sidebar\" class=\"the-media-object m-modeMobile-2 m-modeDesktop-2 m-modeXL-2\" data-nid=\"2885890\" data-cid=\"9720366\" data-part-label=\"Partner content\">\n<figure id=\"abe-2885890-label-pos2-c-latest-stories-sidebar\" class=\"the-media-object__figure\"><img decoding=\"async\" class=\"the-media-object__image\" src=\"https:\/\/images.euronews.com\/articles\/stories\/09\/72\/03\/66\/189x106_cmsv2_a7ca3458-a794-595b-8d2b-91823c43f8cd-9720366.jpg\" loading=\"lazy\" alt=\"Hungarian Prime Minister Viktor Orb\u00e1n.\" height=\"9\" width=\"16\"><\/figure>\n<div class=\"the-media-object__content\">\n                    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<\/p><\/div>\n<\/div>\n<\/article>\n<article class=\"helper-site-row o-article-newsy\">\n<div class=\"helper-site-container o-article-newsy__container\">\n<div class=\"o-article-newsy__main\">\n<header class=\"h-grid o-article-newsy__main__header\">\n<nav aria-label=\"Breadcrumbs\" class=\"c-article-breadcrumbs\">\n<div id=\"adb-article-breadcrumb\" class=\"c-article-breadcrumbs__list\">\n<p>                          Health<\/p>\n<p>                          Health news<\/p><\/div>\n<\/nav>\n<h1 class=\"c-article-redesign-title\">\n                            AI fails at primary patient diagnosis more than 80% of the time, study finds<\/h1>\n<div class=\"c-article-image-video u-position-relative \">\n<div class=\"js-superdiv u-aspect-ratio-16x9 u-position-relative \" data-sponsored=\"Partner content\"><img fetchpriority=\"high\" decoding=\"async\" class=\"js-poster-img c-article-media__img\" src=\"https:\/\/images.euronews.com\/articles\/stories\/09\/72\/02\/63\/1536x864_cmsv2_27833b7a-bb6b-5ca1-bacf-fc8b2a496bf4-9720263.jpg\" width=\"1536\" height=\"864\" loading=\"eager\" alt=\"Study suggests AI chatbots are not ready for frontline clinical use.\"><\/div>\n<div class=\"c-article-caption u-position-absolute\"><i id=\"article-caption-content\" class=\"c-article-caption__content\"><span class=\"c-article-caption__text\"><br \/>\n              Study suggests AI chatbots are not ready for frontline clinical use.<br \/>\n                    <span class=\"u-color-white\">&#8211;\u00a0<\/span><span class=\"c-article-caption__copyright\">Copyright\u00a0<\/span><span class=\"c-article-caption__credit\">Cleared\/Canva<\/span><\/span><\/i><\/div>\n<div class=\"c-article-image-copyright c-article-image-copyright--novideo\">\n      Copyright\u00a0Cleared\/Canva\n  <\/div>\n<\/div>\n<\/header>\n<div class=\"h-grid o-article-newsy__main__body u-article-content\">\n<div class=\"o-article-newsy__contributors-publication-date\">\n<div class=\"c-article-contributors\">\n  By&amp;nbspMarta Iraola Iribarren\n<\/div>\n<div class=\"c-article-publication-date\" data-timestamp=\"1776142843\">\n         Published on<br \/>\n            <time datetime=\"2026-04-14 07:00:43 +02:00\">14\/04\/2026 &#8211; 7:00 GMT+2<\/time><\/div>\n<\/div>\n<div class=\"c-article-partage-commentaire u-align-items-center u-display-flex\"><span class=\"c-article-partage-commentaire__links u-align-items-center u-display-flex u-justify-content-center js-c-article-partage-commentaire-share\"><span>Share<\/span><\/span><span>Comments<\/span><\/div>\n<div class=\"c-article-partage-commentaire-popup-overlay js-c-article-partage-commentaire-popup-overlay u-display-none\">\n<div id=\"js-c-article-partage-commentaire-popup\" class=\"c-article-partage-commentaire-popup js-c-article-partage-commentaire-popup\">\n<div class=\"c-article-partage-commentaire-popup__header 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alt=\"messenger\" class=\"u-show-for-desktop\" loading=\"lazy\"><span class=\"u-display-flex u-gap-1 u-show-for-mobile-only\"><img decoding=\"async\" src=\"https:\/\/static.euronews.com\/website\/images\/vector\/social-icons\/article-redesign-telegram.svg\" width=\"24\" height=\"24\" alt=\"telegram\" loading=\"lazy\"><span>Telegram<\/span><\/span><img decoding=\"async\" src=\"https:\/\/static.euronews.com\/website\/images\/vector\/social-icons\/article-redesign-telegram.svg\" width=\"48\" height=\"48\" alt=\"telegram\" class=\"u-show-for-desktop\" loading=\"lazy\"><span class=\"u-display-flex u-gap-1 u-show-for-mobile-only\"><img decoding=\"async\" src=\"https:\/\/static.euronews.com\/website\/images\/vector\/social-icons\/article-redesign-vk.svg\" width=\"24\" height=\"24\" alt=\"vk\" loading=\"lazy\"><span>VK<\/span><\/span><img decoding=\"async\" src=\"https:\/\/static.euronews.com\/website\/images\/vector\/social-icons\/article-redesign-vk.svg\" width=\"48\" height=\"48\" alt=\"vk\" class=\"u-show-for-desktop\" loading=\"lazy\"><span class=\"u-display-flex u-gap-1 u-show-for-mobile-only\"><img decoding=\"async\" src=\"https:\/\/static.euronews.com\/website\/images\/vector\/social-icons\/article-redesign-bluesky.svg\" width=\"24\" height=\"24\" alt=\"bluesky\" loading=\"lazy\"><span>Bluesky<\/span><\/span><img decoding=\"async\" src=\"https:\/\/static.euronews.com\/website\/images\/vector\/social-icons\/article-redesign-bluesky.svg\" width=\"48\" height=\"48\" alt=\"bluesky\" class=\"u-show-for-desktop\" loading=\"lazy\"><span class=\"u-display-flex u-gap-1 u-show-for-mobile-only\"><img decoding=\"async\" src=\"https:\/\/static.euronews.com\/website\/images\/vector\/social-icons\/article-redesign-threads.svg\" width=\"24\" height=\"24\" alt=\"threads\" loading=\"lazy\"><span>Threads<\/span><\/span><img decoding=\"async\" src=\"https:\/\/static.euronews.com\/website\/images\/vector\/social-icons\/article-redesign-threads.svg\" width=\"48\" height=\"48\" alt=\"threads\" class=\"u-show-for-desktop\" loading=\"lazy\"><span class=\"u-display-flex u-gap-1 u-show-for-mobile-only\"><img decoding=\"async\" src=\"https:\/\/static.euronews.com\/website\/images\/vector\/social-icons\/article-redesign-whatsapp.svg\" width=\"24\" height=\"24\" alt=\"whatsapp\" loading=\"lazy\"><span>Whatsapp<\/span><\/span><img decoding=\"async\" src=\"https:\/\/static.euronews.com\/website\/images\/vector\/social-icons\/article-redesign-whatsapp.svg\" width=\"48\" height=\"48\" alt=\"whatsapp\" class=\"u-show-for-desktop\" loading=\"lazy\"><\/div>\n<\/div>\n<\/div>\n<\/div>\n<h2 class=\"c-article-summary\">\n        AI language models fail to produce an appropriate early diagnosis more than 80% of the time, suggesting they are not yet safe for unsupervised clinical use, according to a new study.<br \/>\n    <\/h2>\n<div class=\"c-article-content c-article-content--health js-article-content\">\n<p>Generative artificial intelligence (AI) still lacks the reasoning processes needed for safe clinical use, a new study has found. <\/p>\n<div>\n<div class=\"c-ad u-show-for-mobile-only\">\n<div class=\"c-ad__placeholder\"><img decoding=\"async\" class=\"c-ad__placeholder__logo\" src=\"https:\/\/static.euronews.com\/website\/images\/logos\/logo-euronews-stacked-outlined-72x72-grey-9.svg\" width=\"72\" height=\"72\" alt loading=\"lazy\"><span>ADVERTISEMENT<\/span><\/div>\n<\/div>\n<div class=\"c-ad u-show-for-desktop\">\n<div class=\"c-ad__placeholder\"><img decoding=\"async\" class=\"c-ad__placeholder__logo\" src=\"https:\/\/static.euronews.com\/website\/images\/logos\/logo-euronews-stacked-outlined-72x72-grey-9.svg\" width=\"72\" height=\"72\" alt loading=\"lazy\"><span>ADVERTISEMENT<\/span><\/div>\n<\/div>\n<\/div>\n<p>AI chatbots have improved their diagnostic accuracy when presented with comprehensive clinical information, but still failed to produce an appropriate differential diagnosis more than 80% of the time, according to researchers at Mass General Brigham, a Boston-based non-profit hospital and research network and one of the largest health systems in the United States.<\/p>\n<p>The results of the study, published in the open-access JAMA Network Open medical journal, found that large language models\u2019 (LLMs) fall short of the reasoning required for clinical use.<\/p>\n<p>\u201cDespite continued improvements, off-the-shelf large language models are not ready for unsupervised clinical-grade deployment,\u201d said Marc Succi, co-author of the study. <\/p>\n<p>He added that AI cannot yet replicate differential diagnosis, which is central to clinical reasoning, and which he considers the \u201cart of medicine\u201d. <\/p>\n<p>Differential diagnosis is the first step for healthcare professionals to identify a condition, separating it from others with similar symptoms. <\/p>\n<h2>How the models were tested<\/h2>\n<p>The research team analysed the functioning of 21 LLMs, including the latest available versions of Claude, DeepSeek, Gemini, GPT and Grok.<\/p>\n<p>They evaluated the LLMs on 29 standardised clinical vignettes using a newly developed tool called PrIME-LLM. <\/p>\n<p>The tool assesses a model\u2019s ability across different stages of clinical reasoning: conducting an initial diagnosis, ordering appropriate tests, arriving at a final diagnosis, and planning treatment. <\/p>\n<div class=\"c-widget-related\" data-stories-id data-event=\"widget_related\">\n<div class=\"c-widget-related__title\"><b class=\"c-widget-related__title__text\" lang=\"en\">Related<\/b><\/div>\n<ul class=\"c-widget-related__list\">\n<li class=\"c-widget-related__item\">ChatGPT and other AI models believe medical misinformation on social media, study warns<\/li>\n<\/ul>\n<\/div>\n<p>To simulate how clinical cases unfold, the researchers gradually fed the models information, beginning with basics such as a patient\u2019s age, sex and symptoms, before adding physical examination findings and laboratory results. <\/p>\n<p>A differential diagnosis is critical in a real-world clinical setting to advance to the next step. However, in the study, the models were given additional information so that they could proceed to the next stage even if they failed at the differential diagnosis step.<\/p>\n<p>The researchers found that the language models achieved high accuracy on final diagnoses but performed poorly in generating differential diagnoses and navigating uncertainty.<\/p>\n<div class=\"c-widget-related\" data-stories-id data-event=\"widget_related\">\n<div class=\"c-widget-related__title\"><b class=\"c-widget-related__title__text\" lang=\"en\">Related<\/b><\/div>\n<ul class=\"c-widget-related__list\">\n<li class=\"c-widget-related__item\">Should you use ChatGPT to answer your medical concerns? New study urges caution<\/li>\n<\/ul>\n<\/div>\n<p>Study author Arya Rao noted that by evaluating LLMs in a stepwise fashion, research moves past treating them like test-takers and puts them in a doctor\u2019s position. <\/p>\n<p>\u201cThese models are great at naming a final diagnosis once the data is complete, but they struggle at the open-ended start of a case, when there isn&#8217;t much information,\u201d she added. <\/p>\n<p>The researchers found that all of the models failed to produce an appropriate differential diagnosis more than 80% of the time. <\/p>\n<p>On final diagnosis, success rates ranged from around 60% to over 90% depending on the model.<\/p>\n<p>Most of the LLMs showed improved accuracy when provided with laboratory results and imaging in addition to text.<\/p>\n<p>The results identified a top-performing cluster that included Grok 4, GPT-5, GPT-4.5, Claude 4.5 Opus, Gemini 3.0 Flash and Gemini 3.0 Pro. <\/p>\n<h2>Medical professionals are still key<\/h2>\n<p>However, the authors noted that despite version-based improvements and advantages in reasoning-optimised models, off-the-shelf LLMs have not yet achieved the level of intelligence required for safe deployment and remain limited in demonstrating advanced clinical reasoning. <\/p>\n<p>\u201cOur results reinforce that large language models in healthcare continue to require a \u2018human in the loop\u2019 and very close oversight,\u201d Succi noted. <\/p>\n<p>Susana Manso Garc\u00eda, a member of the Artificial Intelligence and Digital Health working group of the Spanish Society of Family and Community Medicine, who was not involved in the study, said the findings carry a clear message for the public. <\/p>\n<p>\u201cThe study itself insists they [language models] should not be used to make clinical decisions without supervision. Therefore, whilst artificial intelligence represents a promising tool, human clinical judgement remains indispensable,\u201d she said. <\/p>\n<p>\u201cThe recommendation for the public is to use these technologies with caution and, when faced with any health concern, always consult a healthcare professional.&#8221;<\/p>\n<\/div>\n<p>                          Go to accessibility shortcuts<\/p>\n<div class=\"c-article-partage-commentaire u-align-items-center u-display-flex\"><span class=\"c-article-partage-commentaire__links u-align-items-center u-display-flex u-justify-content-center js-c-article-partage-commentaire-share\"><span>Share<\/span><\/span><span>Comments<\/span><\/div>\n<div id=\"adb-article-you-might-also-like\" class=\"perf-cv-auto c-article-you-might-also-like\">\n<h2 class=\"c-article-you-might-also-like__title\">\n        Read more<br \/>\n      <\/h2>\n<div class=\"c-article-you-might-also-like__container\">\n<article id=\"abe-2885147-pos0-c-article-you-might-also-like__item\" class=\"the-media-object m-modeMobile-1 m-modeDesktop-1 m-modeXL-1 the-media-object--has-video\" data-nid=\"2885147\" data-cid=\"9717191\" data-part-label=\"Partner content\">\n<figure id=\"abe-2885147-label-pos0-c-article-you-might-also-like__item\" class=\"the-media-object__figure\"><img decoding=\"async\" class=\"the-media-object__image\" src=\"https:\/\/images.euronews.com\/articles\/stories\/09\/71\/71\/91\/480x270_cmsv2_f18900fe-893e-5bd7-9abd-e34727d07c89-9717191.jpg\" loading=\"lazy\" alt=\"Long COVID continues to affect millions of people around the world.\" height=\"9\" width=\"16\"><\/figure>\n<div class=\"the-media-object__content\">\n                    Europe in Motion<\/p>\n<h3 class=\"the-media-object__title  \">\n<p>    How is long COVID impacting the EU\u2019s economy?<br \/>\n  <\/h3>\n<\/div>\n<\/article>\n<article id=\"abe-2885198-pos1-c-article-you-might-also-like__item\" class=\"the-media-object m-modeMobile-1 m-modeDesktop-1 m-modeXL-1\" data-nid=\"2885198\" data-cid=\"9717428\" data-part-label=\"Partner content\">\n<figure id=\"abe-2885198-label-pos1-c-article-you-might-also-like__item\" class=\"the-media-object__figure\"><img decoding=\"async\" class=\"the-media-object__image\" src=\"https:\/\/images.euronews.com\/articles\/stories\/09\/71\/74\/28\/480x270_cmsv2_636d20d1-993d-568f-848b-9a97081e81fe-9717428.jpg\" loading=\"lazy\" alt=\"ASA astronaut, Christina Koch, Artemis II mission specialist, undergoes spacesuit checks inside the crew quarters suit-up room.\" height=\"9\" width=\"16\"><\/figure>\n<div class=\"the-media-object__content\">\n                    Health news<\/p>\n<h3 class=\"the-media-object__title  \">\n<p>    Artemis II is back \u2014 now NASA probes what space did to their bodies<br \/>\n  <\/h3>\n<\/div>\n<\/article>\n<article id=\"abe-2884585-pos2-c-article-you-might-also-like__item\" class=\"the-media-object m-modeMobile-1 m-modeDesktop-1 m-modeXL-1\" data-nid=\"2884585\" data-cid=\"9714250\" data-part-label=\"Partner content\">\n<figure id=\"abe-2884585-label-pos2-c-article-you-might-also-like__item\" class=\"the-media-object__figure\"><img decoding=\"async\" class=\"the-media-object__image\" src=\"https:\/\/images.euronews.com\/articles\/stories\/09\/71\/42\/50\/480x270_cmsv2_1ac2436d-08d3-549f-90b5-7bbb612db1d4-9714250.jpg\" loading=\"lazy\" alt=\"Seven days of meditation linked to measurable brain and immune changes, study finds\" height=\"9\" width=\"16\"><\/figure>\n<div class=\"the-media-object__content\">\n                    wellbeing<\/p>\n<h3 class=\"the-media-object__title  \">\n<p>    What happens to your brain after seven days of meditation?<br \/>\n  <\/h3>\n<\/div>\n<\/article>\n<\/div>\n<\/div>\n<div class=\"perf-cv-auto\">\n<ul id=\"adb-article-tags\" class=\"c-tags-list\">\n<li class=\"c-tags-list__item\">\n<p>    chatbot<\/p>\n<\/li>\n<li class=\"c-tags-list__item\">\n<p>    AI<\/p>\n<\/li>\n<li class=\"c-tags-list__item\">\n<p>    Medicine<\/p>\n<\/li>\n<li class=\"c-tags-list__item\">\n<p>    Health<\/p>\n<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<\/div>\n<aside class=\"o-article-newsy__aside\">\n<div class=\"c-ad-wrapper o-article-newsy__aside__content-1\" data-ad-name=\"adzone-halfpage\">\n<div class=\"c-ad c-ad-halfpage u-show-for-desktop\">\n<div class=\"c-ad__placeholder\"><img loading=\"lazy\" decoding=\"async\" class=\"c-ad__placeholder__logo\" src=\"https:\/\/static.euronews.com\/website\/images\/logos\/logo-euronews-stacked-outlined-72x72-grey-9.svg\" width=\"72\" height=\"72\" alt><span>ADVERTISEMENT<\/span><\/div>\n<\/div>\n<div class=\"c-ad u-show-for-mobile-only\">\n<div class=\"c-ad__placeholder\"><img loading=\"lazy\" decoding=\"async\" class=\"c-ad__placeholder__logo\" src=\"https:\/\/static.euronews.com\/website\/images\/logos\/logo-euronews-stacked-outlined-72x72-grey-9.svg\" width=\"72\" height=\"72\" alt><span>ADVERTISEMENT<\/span><\/div>\n<\/div>\n<\/div>\n<div id=\"adb-article-top-stories\" class=\"perf-cv-auto c-top-stories\">\n<h2 class=\"c-top-stories__title\">Top stories<\/h2>\n<div class=\"c-top-stories__item\">\n<article id=\"abe-2885198-pos2-top-stories\" class=\"the-media-object m-modeMobile-2 m-modeDesktop-2 m-modeXL-2 the-media-object--no-label\" data-nid=\"2885198\" data-cid=\"9717428\" data-part-label=\"Partner content\">\n<figure id=\"abe-2885198-label-pos2-top-stories\" class=\"the-media-object__figure\"><img decoding=\"async\" class=\"the-media-object__image\" src=\"https:\/\/images.euronews.com\/articles\/stories\/09\/71\/74\/28\/320x180_cmsv2_636d20d1-993d-568f-848b-9a97081e81fe-9717428.jpg\" loading=\"lazy\" alt=\"ASA astronaut, Christina Koch, Artemis II mission specialist, undergoes spacesuit checks inside the crew quarters suit-up room.\" height=\"9\" width=\"16\"><\/figure>\n<div class=\"the-media-object__content\">\n<h3 class=\"the-media-object__title  \">\n<p>    Artemis II is back \u2014 now NASA probes what space did to their bodies<br \/>\n  <\/h3>\n<\/div>\n<\/article>\n<\/div>\n<div class=\"c-top-stories__item\">\n<article id=\"abe-2884585-pos3-top-stories\" class=\"the-media-object m-modeMobile-2 m-modeDesktop-2 m-modeXL-2 the-media-object--no-label\" data-nid=\"2884585\" data-cid=\"9714250\" data-part-label=\"Partner content\">\n<figure id=\"abe-2884585-label-pos3-top-stories\" class=\"the-media-object__figure\"><img decoding=\"async\" class=\"the-media-object__image\" src=\"https:\/\/images.euronews.com\/articles\/stories\/09\/71\/42\/50\/320x180_cmsv2_1ac2436d-08d3-549f-90b5-7bbb612db1d4-9714250.jpg\" loading=\"lazy\" alt=\"Seven days of meditation linked to measurable brain and immune changes, study finds\" height=\"9\" width=\"16\"><\/figure>\n<div class=\"the-media-object__content\">\n<h3 class=\"the-media-object__title  \">\n<p>    What happens to your brain after seven days of meditation?<br \/>\n  <\/h3>\n<\/div>\n<\/article>\n<\/div>\n<div class=\"c-top-stories__item\">\n<article id=\"abe-2883295-pos4-top-stories\" class=\"the-media-object m-modeMobile-2 m-modeDesktop-2 m-modeXL-2 the-media-object--no-label\" data-nid=\"2883295\" data-cid=\"9708242\" data-part-label=\"Partner content\">\n<figure id=\"abe-2883295-label-pos4-top-stories\" class=\"the-media-object__figure\"><img decoding=\"async\" class=\"the-media-object__image\" src=\"https:\/\/images.euronews.com\/articles\/stories\/09\/70\/82\/42\/320x180_cmsv2_f2dc1b55-83b9-5e12-b4f9-9c465dc6ab42-9708242.jpg\" loading=\"lazy\" alt=\"People sit under cherry blossoms in St James's Park, in London.\" height=\"9\" width=\"16\"><\/figure>\n<div class=\"the-media-object__content\">\n<h3 class=\"the-media-object__title  \">\n<p>    Pollen season is getting longer. Here\u2019s how to protect yourself<br \/>\n  <\/h3>\n<\/div>\n<\/article>\n<\/div>\n<div class=\"c-top-stories__item\">\n<article id=\"abe-2884693-pos5-top-stories\" class=\"the-media-object m-modeMobile-2 m-modeDesktop-2 m-modeXL-2 the-media-object--no-label\" data-nid=\"2884693\" data-cid=\"9714873\" data-part-label=\"Partner content\">\n<figure id=\"abe-2884693-label-pos5-top-stories\" class=\"the-media-object__figure\"><img decoding=\"async\" class=\"the-media-object__image\" src=\"https:\/\/images.euronews.com\/articles\/stories\/09\/71\/48\/73\/320x180_cmsv2_bcb8898c-25bd-5c15-ad99-f820088fba00-9714873.jpg\" loading=\"lazy\" alt=\"Countries are expected to spend around $11 billion (\u20ac9.40 billion) a year over the next decade to address long COVID-related healthcare costs.\" height=\"9\" width=\"16\"><\/figure>\n<div class=\"the-media-object__content\">\n<h3 class=\"the-media-object__title  \">\n<p>    Long COVID remains a burden on health systems and economies, OECD says<br \/>\n  <\/h3>\n<\/div>\n<\/article>\n<\/div>\n<div class=\"c-top-stories__item\">\n<article id=\"abe-2881730-pos6-top-stories\" class=\"the-media-object m-modeMobile-2 m-modeDesktop-2 m-modeXL-2 the-media-object--no-label\" data-nid=\"2881730\" data-cid=\"9700745\" data-part-label=\"Partner content\">\n<figure id=\"abe-2881730-label-pos6-top-stories\" class=\"the-media-object__figure\"><img decoding=\"async\" class=\"the-media-object__image\" src=\"https:\/\/images.euronews.com\/articles\/stories\/09\/70\/07\/45\/320x180_cmsv2_67ef6d6e-40cc-5b91-bb8b-fe5ca4a0c84f-9700745.jpg\" loading=\"lazy\" alt=\"Could remote work help reverse falling birth rates? New research suggests yes\" height=\"9\" width=\"16\"><\/figure>\n<div class=\"the-media-object__content\">\n<h3 class=\"the-media-object__title  \">\n<p>    Working from home is linked to higher fertility, new study finds<br \/>\n  <\/h3>\n<\/div>\n<\/article>\n<\/div>\n<\/div>\n<div class=\"perf-cv-auto c-ad-wrapper o-article-newsy__aside__content-2\" data-ad-name=\"adzone-halfpage\">\n<div class=\"c-ad c-ad-halfpage u-show-for-desktop\">\n<div class=\"c-ad__placeholder\"><img loading=\"lazy\" decoding=\"async\" class=\"c-ad__placeholder__logo\" src=\"https:\/\/static.euronews.com\/website\/images\/logos\/logo-euronews-stacked-outlined-72x72-grey-9.svg\" width=\"72\" height=\"72\" alt><span>ADVERTISEMENT<\/span><\/div>\n<\/div>\n<div class=\"c-ad u-show-for-mobile-only\">\n<div class=\"c-ad__placeholder\"><img loading=\"lazy\" decoding=\"async\" class=\"c-ad__placeholder__logo\" src=\"https:\/\/static.euronews.com\/website\/images\/logos\/logo-euronews-stacked-outlined-72x72-grey-9.svg\" width=\"72\" height=\"72\" alt><span>ADVERTISEMENT<\/span><\/div>\n<\/div>\n<\/div>\n<div class=\"perf-cv-auto c-most-viewed\">\n<h2 class=\"c-most-viewed__title qa-section-title\">Most read<\/h2>\n<div class=\"c-most-viewed__list\">\n<div class=\"c-most-viewed__item\"><span class=\"c-most-viewed__item__number\">1<\/span><\/p>\n<article id=\"abe-2362642-pos1-mostViewed\" class=\"the-media-object m-modeMobile-3 m-modeDesktop-3 m-modeXL-3 the-media-object--has-video the-media-object--has-related the-media-object--no-label\" data-nid=\"2362642\" data-cid=\"7870952\" data-part-label=\"Partner content\">\n<div class=\"the-media-object__content\">\n<h3 class=\"the-media-object__title  \">\n<p>    COVID: Should we fear a new winter wave?<br \/>\n  <\/h3>\n<\/div>\n<\/article>\n<\/div>\n<div class=\"c-most-viewed__item\"><span 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alt><span>ADVERTISEMENT<\/span><\/div>\n<\/div>\n<\/div>\n<\/aside>\n<\/div>\n<\/article>\n<article id=\"abe-2885147-pos0-c-article-you-might-also-like__item\" class=\"the-media-object m-modeMobile-1 m-modeDesktop-1 m-modeXL-1 the-media-object--has-video\" data-nid=\"2885147\" data-cid=\"9717191\" data-part-label=\"Partner content\">\n<figure id=\"abe-2885147-label-pos0-c-article-you-might-also-like__item\" class=\"the-media-object__figure\"><img decoding=\"async\" class=\"the-media-object__image\" src=\"https:\/\/images.euronews.com\/articles\/stories\/09\/71\/71\/91\/480x270_cmsv2_f18900fe-893e-5bd7-9abd-e34727d07c89-9717191.jpg\" loading=\"lazy\" alt=\"Long COVID continues to affect millions of people around the world.\" height=\"9\" width=\"16\"><\/figure>\n<div class=\"the-media-object__content\">\n                    Europe in Motion<\/p>\n<h3 class=\"the-media-object__title  \">\n<p>    How is long COVID impacting the EU\u2019s economy?<br \/>\n  <\/h3>\n<\/div>\n<\/article>\n<article id=\"abe-2885198-pos1-c-article-you-might-also-like__item\" class=\"the-media-object m-modeMobile-1 m-modeDesktop-1 m-modeXL-1\" data-nid=\"2885198\" data-cid=\"9717428\" data-part-label=\"Partner content\">\n<figure id=\"abe-2885198-label-pos1-c-article-you-might-also-like__item\" class=\"the-media-object__figure\"><img decoding=\"async\" class=\"the-media-object__image\" src=\"https:\/\/images.euronews.com\/articles\/stories\/09\/71\/74\/28\/480x270_cmsv2_636d20d1-993d-568f-848b-9a97081e81fe-9717428.jpg\" loading=\"lazy\" alt=\"ASA astronaut, Christina Koch, Artemis II mission specialist, undergoes spacesuit checks inside the crew quarters suit-up room.\" height=\"9\" width=\"16\"><\/figure>\n<div class=\"the-media-object__content\">\n                    Health news<\/p>\n<h3 class=\"the-media-object__title  \">\n<p>    Artemis II is back \u2014 now NASA probes what space did to their bodies<br \/>\n  <\/h3>\n<\/div>\n<\/article>\n<article id=\"abe-2884585-pos2-c-article-you-might-also-like__item\" class=\"the-media-object m-modeMobile-1 m-modeDesktop-1 m-modeXL-1\" data-nid=\"2884585\" data-cid=\"9714250\" data-part-label=\"Partner content\">\n<figure id=\"abe-2884585-label-pos2-c-article-you-might-also-like__item\" class=\"the-media-object__figure\"><img decoding=\"async\" class=\"the-media-object__image\" src=\"https:\/\/images.euronews.com\/articles\/stories\/09\/71\/42\/50\/480x270_cmsv2_1ac2436d-08d3-549f-90b5-7bbb612db1d4-9714250.jpg\" loading=\"lazy\" alt=\"Seven days of meditation linked to measurable brain and immune changes, study finds\" height=\"9\" width=\"16\"><\/figure>\n<div class=\"the-media-object__content\">\n                    wellbeing<\/p>\n<h3 class=\"the-media-object__title  \">\n<p>    What happens to your brain after seven days of meditation?<br \/>\n  <\/h3>\n<\/div>\n<\/article>\n<article id=\"abe-2885198-pos2-top-stories\" class=\"the-media-object m-modeMobile-2 m-modeDesktop-2 m-modeXL-2 the-media-object--no-label\" data-nid=\"2885198\" data-cid=\"9717428\" data-part-label=\"Partner content\">\n<figure id=\"abe-2885198-label-pos2-top-stories\" class=\"the-media-object__figure\"><img decoding=\"async\" class=\"the-media-object__image\" src=\"https:\/\/images.euronews.com\/articles\/stories\/09\/71\/74\/28\/320x180_cmsv2_636d20d1-993d-568f-848b-9a97081e81fe-9717428.jpg\" loading=\"lazy\" alt=\"ASA astronaut, Christina Koch, Artemis II mission specialist, undergoes spacesuit checks inside the crew quarters suit-up room.\" height=\"9\" width=\"16\"><\/figure>\n<div class=\"the-media-object__content\">\n<h3 class=\"the-media-object__title  \">\n<p>    Artemis II is back \u2014 now NASA probes what space did to their bodies<br \/>\n  <\/h3>\n<\/div>\n<\/article>\n<article id=\"abe-2884585-pos3-top-stories\" class=\"the-media-object m-modeMobile-2 m-modeDesktop-2 m-modeXL-2 the-media-object--no-label\" data-nid=\"2884585\" data-cid=\"9714250\" data-part-label=\"Partner content\">\n<figure id=\"abe-2884585-label-pos3-top-stories\" class=\"the-media-object__figure\"><img decoding=\"async\" class=\"the-media-object__image\" src=\"https:\/\/images.euronews.com\/articles\/stories\/09\/71\/42\/50\/320x180_cmsv2_1ac2436d-08d3-549f-90b5-7bbb612db1d4-9714250.jpg\" loading=\"lazy\" alt=\"Seven days of meditation linked to measurable brain and immune changes, study finds\" height=\"9\" width=\"16\"><\/figure>\n<div class=\"the-media-object__content\">\n<h3 class=\"the-media-object__title  \">\n<p>    What happens to your brain after seven days of meditation?<br \/>\n  <\/h3>\n<\/div>\n<\/article>\n<article id=\"abe-2883295-pos4-top-stories\" class=\"the-media-object m-modeMobile-2 m-modeDesktop-2 m-modeXL-2 the-media-object--no-label\" data-nid=\"2883295\" data-cid=\"9708242\" data-part-label=\"Partner content\">\n<figure id=\"abe-2883295-label-pos4-top-stories\" class=\"the-media-object__figure\"><img decoding=\"async\" class=\"the-media-object__image\" src=\"https:\/\/images.euronews.com\/articles\/stories\/09\/70\/82\/42\/320x180_cmsv2_f2dc1b55-83b9-5e12-b4f9-9c465dc6ab42-9708242.jpg\" loading=\"lazy\" alt=\"People sit under cherry blossoms in St James's Park, in London.\" height=\"9\" width=\"16\"><\/figure>\n<div class=\"the-media-object__content\">\n<h3 class=\"the-media-object__title  \">\n<p>    Pollen season is getting longer. Here\u2019s how to protect yourself<br \/>\n  <\/h3>\n<\/div>\n<\/article>\n<article id=\"abe-2884693-pos5-top-stories\" class=\"the-media-object m-modeMobile-2 m-modeDesktop-2 m-modeXL-2 the-media-object--no-label\" data-nid=\"2884693\" data-cid=\"9714873\" data-part-label=\"Partner content\">\n<figure id=\"abe-2884693-label-pos5-top-stories\" class=\"the-media-object__figure\"><img decoding=\"async\" class=\"the-media-object__image\" src=\"https:\/\/images.euronews.com\/articles\/stories\/09\/71\/48\/73\/320x180_cmsv2_bcb8898c-25bd-5c15-ad99-f820088fba00-9714873.jpg\" loading=\"lazy\" alt=\"Countries are expected to spend around $11 billion (\u20ac9.40 billion) a year over the next decade to address long COVID-related healthcare costs.\" height=\"9\" width=\"16\"><\/figure>\n<div class=\"the-media-object__content\">\n<h3 class=\"the-media-object__title  \">\n<p>    Long COVID remains a burden on health systems and economies, OECD says<br \/>\n  <\/h3>\n<\/div>\n<\/article>\n<article id=\"abe-2881730-pos6-top-stories\" class=\"the-media-object m-modeMobile-2 m-modeDesktop-2 m-modeXL-2 the-media-object--no-label\" data-nid=\"2881730\" data-cid=\"9700745\" data-part-label=\"Partner content\">\n<figure id=\"abe-2881730-label-pos6-top-stories\" class=\"the-media-object__figure\"><img decoding=\"async\" class=\"the-media-object__image\" src=\"https:\/\/images.euronews.com\/articles\/stories\/09\/70\/07\/45\/320x180_cmsv2_67ef6d6e-40cc-5b91-bb8b-fe5ca4a0c84f-9700745.jpg\" loading=\"lazy\" alt=\"Could remote work help reverse falling birth rates? New research suggests yes\" height=\"9\" width=\"16\"><\/figure>\n<div class=\"the-media-object__content\">\n<h3 class=\"the-media-object__title  \">\n<p>    Working from home is linked to higher fertility, new study finds<br \/>\n  <\/h3>\n<\/div>\n<\/article>\n<article id=\"abe-2362642-pos1-mostViewed\" class=\"the-media-object m-modeMobile-3 m-modeDesktop-3 m-modeXL-3 the-media-object--has-video the-media-object--has-related the-media-object--no-label\" data-nid=\"2362642\" data-cid=\"7870952\" data-part-label=\"Partner content\">\n<div class=\"the-media-object__content\">\n<h3 class=\"the-media-object__title  \">\n<p>    COVID: Should we fear a new winter wave?<br \/>\n  <\/h3>\n<\/div>\n<\/article>\n<article id=\"abe-2885873-pos2-mostViewed\" class=\"the-media-object m-modeMobile-3 m-modeDesktop-3 m-modeXL-3 the-media-object--has-related the-media-object--no-label\" data-nid=\"2885873\" data-cid=\"9720263\" data-part-label=\"Partner content\">\n<div class=\"the-media-object__content\">\n<h3 class=\"the-media-object__title  \">\n<p>    AI fails at primary diagnosis more than 80% of the time, study finds<br \/>\n  <\/h3>\n<\/div>\n<\/article>\n<article id=\"abe-2440852-pos3-mostViewed\" class=\"the-media-object m-modeMobile-3 m-modeDesktop-3 m-modeXL-3 the-media-object--has-related the-media-object--no-label\" data-nid=\"2440852\" data-cid=\"8124816\" data-part-label=\"Partner content\">\n<div class=\"the-media-object__content\">\n<h3 class=\"the-media-object__title  \">\n<p>    Scientists discover first new antibiotics in over 60 years using AI<br \/>\n  <\/h3>\n<\/div>\n<\/article>\n<article id=\"abe-2885198-pos4-mostViewed\" class=\"the-media-object m-modeMobile-3 m-modeDesktop-3 m-modeXL-3 the-media-object--has-related the-media-object--no-label\" data-nid=\"2885198\" data-cid=\"9717428\" data-part-label=\"Partner content\">\n<div class=\"the-media-object__content\">\n<h3 class=\"the-media-object__title  \">\n<p>    Artemis II is back \u2014 now NASA probes what space did to their bodies<br \/>\n  <\/h3>\n<\/div>\n<\/article>\n<article id=\"abe-2884585-pos5-mostViewed\" class=\"the-media-object m-modeMobile-3 m-modeDesktop-3 m-modeXL-3 the-media-object--has-related the-media-object--no-label\" data-nid=\"2884585\" data-cid=\"9714250\" data-part-label=\"Partner content\">\n<div class=\"the-media-object__content\">\n<h3 class=\"the-media-object__title  \">\n<p>    What happens to your brain after seven days of meditation?<br \/>\n  <\/h3>\n<\/div>\n<\/article>\n<div class=\"articleBody\" data-key=\"articleBody\">Generative artificial intelligence (AI) still lacks the reasoning processes needed for safe clinical use, a new study has found.\u00a0AI chatbots have improved their diagnostic accuracy when presented with comprehensive clinical information, but still failed to produce an appropriate differential diagnosis more than 80% of the time, according to researchers at Mass General Brigham, a Boston-based non-profit hospital and research network and one of the largest health systems in the United States.The results of the study, published in the open-access JAMA Network Open medical journal, found that large language models\u2019 (LLMs) fall short of the reasoning required for clinical use.\u201cDespite continued improvements, off-the-shelf large language models are not ready for unsupervised clinical-grade deployment,\u201d said Marc Succi, co-author of the study.\u00a0\u00a0He added that AI cannot yet replicate differential diagnosis, which is central to clinical reasoning, and which he considers the \u201cart of medicine\u201d.\u00a0Differential diagnosis is the first step for healthcare professionals to identify a condition, separating it from others with similar symptoms.\u00a0How the models were testedThe research team analysed the functioning of 21 LLMs, including the latest available versions of Claude, DeepSeek, Gemini, GPT and Grok.They evaluated the LLMs on 29 standardised clinical vignettes using a newly developed tool called PrIME-LLM.The tool assesses a model\u2019s ability across different stages of clinical reasoning: conducting an initial diagnosis, ordering appropriate tests, arriving at a final diagnosis, and planning treatment.\u00a0To simulate how clinical cases unfold, the researchers gradually fed the models information, beginning with basics such as a patient\u2019s age, sex and symptoms, before adding physical examination findings and laboratory results.\u00a0A differential diagnosis is critical in a real-world clinical setting to advance to the next step. However, in the study, the models were given additional information so that they could proceed to the next stage even if they failed at the differential diagnosis step.The researchers found that the language models achieved high accuracy on final diagnoses but performed poorly in generating differential diagnoses and navigating uncertainty.Study author Arya Rao noted that by evaluating LLMs in a stepwise fashion, research moves past treating them like test-takers and puts them in a doctor\u2019s position.\u00a0\u201cThese models are great at naming a final diagnosis once the data is complete, but they struggle at the open-ended start of a case, when there isn&#8217;t much information,\u201d she added.\u00a0The researchers found that all of the models failed to produce an appropriate differential diagnosis more than 80% of the time.\u00a0On final diagnosis, success rates ranged from around 60% to over 90% depending on the model.Most of the LLMs showed improved accuracy when provided with laboratory results and imaging in addition to text.The results identified a top-performing cluster that included Grok 4, GPT-5, GPT-4.5, Claude 4.5 Opus, Gemini 3.0 Flash and Gemini 3.0 Pro.\u00a0Medical professionals are still keyHowever, the authors noted that despite version-based improvements and advantages in reasoning-optimised models, off-the-shelf LLMs have not yet achieved the level of intelligence required for safe deployment and remain limited in demonstrating advanced clinical reasoning.\u00a0\u201cOur results reinforce that large language models in healthcare continue to require a \u2018human in the loop\u2019 and very close oversight,\u201d Succi noted.\u00a0\u00a0Susana Manso Garc\u00eda, a member of the Artificial Intelligence and Digital Health working group of the Spanish Society of Family and Community Medicine, who was not involved in the study, said the findings carry a clear message for the public.\u00a0\u201cThe study itself insists they [language models] should not be used to make clinical decisions without supervision. Therefore, whilst artificial intelligence represents a promising tool, human clinical judgement remains indispensable,\u201d she said.\u00a0\u201cThe recommendation for the public is to use these technologies with caution and, when faced with any health concern, always consult a healthcare professional.&#8221;<\/div>\n<p>[analyse_source url=&#8221;https:\/\/www.euronews.com\/health\/2026\/04\/14\/ai-fails-at-primary-patient-diagnosis-more-than-80-of-the-time-study-finds&#8221;]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>[analyse_image type=&#8221;featured&#8221; src=&#8221;https:\/\/images.euronews.com\/articles\/stories\/09\/72\/02\/63\/1200x675_cmsv2_27833b7a-bb6b-5ca1-bacf-fc8b2a496bf4-9720263.jpg&#8221;] Europe Today Live. After historic Israel\u2013Lebanon talks, is a ceasefire within reach? Europe News Life after Orb\u00e1n: How his defeat is set to transform EU power dynamics Top News Stories Today Latest news bulletin | April 15th, 2026 \u2013 Morning Economy Rent surges in Europe: Where did prices rise most in 2025? 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