{"id":1700905,"date":"2026-01-19T13:15:00","date_gmt":"2026-01-19T10:15:00","guid":{"rendered":"https:\/\/analyse.optim.biz\/?p=1700905"},"modified":"2026-01-19T13:15:00","modified_gmt":"2026-01-19T10:15:00","slug":"is-it-safe-to-use-hyaluronic-acid-with-retinol-dermatologists-weigh-in","status":"publish","type":"post","link":"https:\/\/analyse.optim.biz\/?p=1700905","title":{"rendered":"Is It Safe to Use Hyaluronic Acid With Retinol? Dermatologists Weigh In"},"content":{"rendered":"<p><main id=\"main_1-0\" class=\"comp main layout-body--continuous-scroll mntl-block\" data-tracking-container=\"true\"><\/p>\n<article id=\"beauty-article--sc_1-0\" class=\"comp beauty-article--sc beauty-article mntl-article mntl-article--three-column sc-ad-container\" data-tracking-container=\"true\">\n<div class=\"loc article-header\">\n<div id=\"article-header_1-0\" class=\"comp article-header mntl-block article-top\">\n<h1 id=\"article-heading_1-0\" class=\"comp article-heading mntl-text-block\">Is It Safe to Use Hyaluronic Acid With Retinol? Dermatologists Weigh In<\/h1>\n<p id=\"article-subheading_1-0\" class=\"comp article-subheading mntl-text-block\">Hint: You&#8217;re probably already mixing them.<\/p>\n<div id=\"article-meta_1-0\" class=\"comp article-meta mntl-article-meta mntl-block\" data-tracking-container=\"true\">\n<div id=\"bylines_1-0\" class=\"comp bylines beauty-bylines mntl-bylines\" data-tracking-container=\"true\">\n<div id=\"mntl-bylines__group_1-0\" class=\"comp mntl-bylines__group mntl-block mntl-bylines__group--author\">\n<div id=\"mntl-bylines__item_1-0\" class=\"comp mntl-bylines__item mntl-attribution__item mntl-attribution__item--has-date\"><span class=\"mntl-attribution__item-descriptor\">By<\/span><\/p>\n<div data-tooltip=\"Dani is New York-based beauty writer and editor. Her work has been featured in Allure, Elle, InStyle, Well + Good, and more.\" data-inline-tooltip=\"true\"> Dani Hardman<\/p>\n<div id=\"mntl-author-tooltip_1-0\" class=\"comp mntl-author-tooltip mntl-tooltip mntl-group\">\n<div class=\"mntl-author-tooltip__top \">\n<div class=\"mntl-author-tooltip__image-wrapper\">\n<div class=\"img-placeholder\"><img loading=\"lazy\" decoding=\"async\" width=\"200\" height=\"200\" alt=\"Danielle Cohen\" class=\"lazyload mntl-author-tooltip__image mntl-image universal-image__image\" src=\"https:\/\/analyse.optim.biz\/wp-content\/uploads\/2026\/02\/byrdieimagesize-130b5be39471413aa98b61be592acaa3-5.webp\" title=\"byrdieimagesize-130b5be39471413aa98b61be592acaa3-5\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/analyse.optim.biz\/wp-content\/uploads\/2026\/02\/byrdieimagesize-130b5be39471413aa98b61be592acaa3-5.webp\" width=\"200\" height=\"200\" class=\"img--noscript mntl-author-tooltip__image mntl-image universal-image__image\" alt=\"Danielle Cohen\" title=\"byrdieimagesize-130b5be39471413aa98b61be592acaa3-5\"><\/div>\n<\/div>\n<div id=\"mntl-author-tooltip__name_1-0\" class=\"comp mntl-author-tooltip__name mntl-attribution__item \">\nDani Hardman\n<\/div>\n<div id=\"mntl-author-tooltip__social-nav_1-0\" class=\"comp mntl-author-tooltip__social-nav beauty-social-nav mntl-social-nav social-nav--tooltip\" data-tracking-container=\"true\">\n<ul class=\"social-nav__list\">\n<li class=\"social-nav__item social-nav__item--instagram\">\n<li class=\"social-nav__item social-nav__item--linkedin\"><\/ul>\n<\/div>\n<div class=\"mntl-author-tooltip__bio\">\nDani is New York-based beauty writer and editor. Her work has been featured in Allure, Elle, InStyle, Well + Good, and more.\n<\/div>\n<\/div>\n<div class=\"mntl-author-tooltip__bottom\">\nByrdie&#8217;s Editorial Guidelines\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"mntl-attribution__item-date\">Published on January 19, 2026 08:15AM<\/div>\n<\/div>\n<div id=\"mntl-bylines__group_2-0\" class=\"comp mntl-bylines__group mntl-block mntl-bylines__group--beauty_wellness_reviewer\">\n<div id=\"mntl-bylines__item_2-0\" class=\"comp mntl-bylines__item mntl-attribution__item \"><span class=\"mntl-attribution__item-descriptor\">Reviewed by<\/span><\/p>\n<div data-tooltip=\"Julia A. Siegel, MD is a board-certified dermatologist based in Boston, Massachusetts. She is a member of the American Academy of Dermatology and has authored several peer-reviewed journal articles and book chapters.\u00a0\" data-inline-tooltip=\"true\"> Julia A. Siegel, MD<\/p>\n<div id=\"mntl-author-tooltip_2-0\" class=\"comp mntl-author-tooltip mntl-tooltip mntl-group\">\n<div class=\"mntl-author-tooltip__top \">\n<div class=\"mntl-author-tooltip__image-wrapper\">\n<div class=\"img-placeholder\"><img loading=\"lazy\" decoding=\"async\" width=\"200\" height=\"200\" alt=\"Julia Siegel\" class=\"lazyload mntl-author-tooltip__image mntl-image universal-image__image\" src=\"https:\/\/analyse.optim.biz\/wp-content\/uploads\/2026\/02\/juliasiegel-e3dee3e76304428b9357e4fe8da1a50b-12.webp\" title=\"juliasiegel-e3dee3e76304428b9357e4fe8da1a50b-12\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/analyse.optim.biz\/wp-content\/uploads\/2026\/02\/juliasiegel-e3dee3e76304428b9357e4fe8da1a50b-12.webp\" width=\"200\" height=\"200\" class=\"img--noscript mntl-author-tooltip__image mntl-image universal-image__image\" alt=\"Julia Siegel\" title=\"juliasiegel-e3dee3e76304428b9357e4fe8da1a50b-12\"><\/div>\n<\/div>\n<div id=\"mntl-author-tooltip__name_2-0\" class=\"comp mntl-author-tooltip__name mntl-attribution__item \"><span class=\"mntl-attribution__item-descriptor\">Reviewed by<\/span><br \/>\nJulia A. Siegel, MD\n<\/div>\n<div class=\"mntl-author-tooltip__bio\">\nJulia A. Siegel, MD is a board-certified dermatologist based in Boston, Massachusetts. She is a member of the American Academy of Dermatology and has authored several peer-reviewed journal articles and book chapters.\u00a0\n<\/div>\n<\/div>\n<div class=\"mntl-author-tooltip__bottom\">\nAbout Byrdie&#8217;s Beauty &amp; Wellness Board\n<\/div>\n<\/div>\n<\/div>\n<div class=\"mntl-attribution__item-postscript\">Board-Certified Dermatologist<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"loc article-left-rail\">\n<div id=\"beauty-sticky-toc_1-0\" class=\"comp beauty-sticky-toc mntl-block js-sticky-container sticky-toc__wrapper\">\n<div id=\"sticky-toc_1-0\" class=\"comp sticky-toc mntl-universal-sticky-toc mntl-sticky-toc mntl-block sticky-toc-widget\" data-desktop-bp=\"70em\">\n<div id=\"toc-wrapper_1-0\" class=\"comp toc-wrapper mntl-toc mntl-block\" data-chop-mobile=\"true\" data-offset=\"60\" data-tracking-container=\"true\">\n<div id=\"mntl-toc__inner_1-0\" class=\"comp mntl-toc__inner mntl-block\">\n<div id=\"mntl-toc__heading_1-0\" class=\"comp mntl-toc__heading mntl-block js-toc-toggle\"><span id=\"mntl-toc__heading-text_1-0\" class=\"comp mntl-toc__heading-text mntl-text-block\">In This Article<\/span><\/p>\n<div id=\"mntl-toc-toggle_1-0\" class=\"comp mntl-toc-toggle mntl-block\">\n<div id=\"mntl-toc-toggle__btn_1-0\" class=\"comp mntl-toc-toggle__btn mntl-text-block js-mntl-toc-toggle text-label-300\" data-click-tracked=\"true\" data-collapsed-text=\"View All\" data-expanded-text=\"View Less\">View All<\/div>\n<\/div>\n<\/div>\n<div id=\"mntl-toc__mobile-toggle_1-0\" class=\"comp mntl-toc__mobile-toggle mntl-block js-sticky-toggle\"><span id=\"mntl-toc__heading-text_2-0\" class=\"comp mntl-toc__heading-text mntl-text-block\">In This Article<\/span><\/div>\n<ul id=\"mntl-toc__list_1-0\" class=\"comp mntl-toc__list mntl-toc__list-heading expert-content text-utility-300\">\n<li id=\"mntl-toc__list-item_1-0\" class=\"comp mntl-toc__list-item mntl-block\">\n<div id=\"mntl-toc__list-item-heading_1-0\" class=\"comp mntl-toc__list-item-heading mntl-block\"><span class=\"link__wrapper\">What Is Hyaluronic Acid?<\/span><\/div>\n<\/li>\n<li id=\"mntl-toc__list-item_2-0\" class=\"comp mntl-toc__list-item mntl-block\">\n<div id=\"mntl-toc__list-item-heading_2-0\" class=\"comp mntl-toc__list-item-heading mntl-block\"><span class=\"link__wrapper\">What Is Retinol?<\/span><\/div>\n<\/li>\n<li id=\"mntl-toc__list-item_3-0\" class=\"comp mntl-toc__list-item mntl-block\">\n<div id=\"mntl-toc__list-item-heading_3-0\" class=\"comp mntl-toc__list-item-heading mntl-block\"><span class=\"link__wrapper\">Can You Use Them Together?<\/span><\/div>\n<\/li>\n<li id=\"mntl-toc__list-item_4-0\" class=\"comp mntl-toc__list-item mntl-block\">\n<div id=\"mntl-toc__list-item-heading_4-0\" class=\"comp mntl-toc__list-item-heading mntl-block\"><span class=\"link__wrapper\">Benefits<\/span><\/div>\n<\/li>\n<li id=\"mntl-toc__list-item_5-0\" class=\"comp mntl-toc__list-item mntl-block\">\n<div id=\"mntl-toc__list-item-heading_5-0\" class=\"comp mntl-toc__list-item-heading mntl-block\"><span class=\"link__wrapper\">Side Effects<\/span><\/div>\n<\/li>\n<li id=\"mntl-toc__list-item_6-0\" class=\"comp mntl-toc__list-item mntl-block\">\n<div id=\"mntl-toc__list-item-heading_6-0\" class=\"comp mntl-toc__list-item-heading mntl-block\"><span class=\"link__wrapper\">How to Use Together<\/span><\/div>\n<\/li>\n<li id=\"mntl-toc__list-item_7-0\" class=\"comp mntl-toc__list-item mntl-block\">\n<div id=\"mntl-toc__list-item-heading_7-0\" class=\"comp mntl-toc__list-item-heading mntl-block\"><span class=\"link__wrapper\">Minimize Irritation<\/span><\/div>\n<\/li>\n<li id=\"mntl-toc__list-item_8-0\" class=\"comp mntl-toc__list-item mntl-block\">\n<div id=\"mntl-toc__list-item-heading_8-0\" class=\"comp mntl-toc__list-item-heading mntl-block\"><span class=\"link__wrapper\">The Final Takeaway<\/span><\/div>\n<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"loc article-content\">\n<div id=\"article__broad-video-jw_1-0\" class=\"comp article__broad-video-jw mntl-jwplayer-broad mntl-block is-hidden\" data-pixel-depth=\"100\">\n<div id=\"mntl-jwplayer-broad__title_1-0\" class=\"comp mntl-jwplayer-broad__title mntl-block\"><button id=\"mntl-jwplayer-broad__title-icon--close_1-0\" class=\"comp mntl-jwplayer-broad__title-icon--close mntl-block text-label-100\" data-click-tracked=\"false\"><span id=\"mntl-text-block_2-0\" class=\"comp mntl-text-block\">Close<\/span><\/button><\/div>\n<\/div>\n<div id=\"mntl-block_2-0\" class=\"comp mntl-block article__body right-rail\">\n<figure id=\"mntl-universal-primary-image_1-0\" class=\"comp mntl-universal-primary-image primary-image\" data-tracking-container=\"true\">\n<div class=\"primary-image__media\">\n<div class=\"img-placeholder\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/analyse.optim.biz\/wp-content\/uploads\/2026\/02\/skincare-2-a9b87ad2a2b142379b8bf91d791cc5d1-4.webp\" width=\"1280\" height=\"960\" alt=\"A closeup of an open skincare tube with product visible at the top\" class=\" primary-image__image mntl-primary-image--blurry\" title=\"skincare-2-a9b87ad2a2b142379b8bf91d791cc5d1-4\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/analyse.optim.biz\/wp-content\/uploads\/2026\/02\/skincare-2-a9b87ad2a2b142379b8bf91d791cc5d1-4.webp\" width=\"1280\" height=\"960\" class=\"loaded primary-img--noscript primary-image__image mntl-primary-image--blurry\" alt=\"A closeup of an open skincare tube with product visible at the top\" title=\"skincare-2-a9b87ad2a2b142379b8bf91d791cc5d1-4\"><\/div>\n<\/div><figcaption id=\"primary-image__figcap_1-0\" class=\"comp primary-image__figcap mntl-figure-caption figure-article-caption\"><span class=\"figure-article-caption-owner\"><\/p>\n<p>Death to Stock<\/p>\n<p><\/span><\/figcaption><\/figure>\n<div id=\"mntl-sc-page_1-0\" class=\"comp mntl-sc-page mntl-block\" data-sc-sticky-offset=\"125\" data-sc-ad-label-height=\"16\" data-sc-ad-track-spacing=\"100\" data-sc-min-track-height=\"250\" data-sc-max-track-height=\"600\" data-sc-breakpoint=\"50em\" data-sc-load-immediate=\"5\" data-sc-content-positions=\"[1, 1250, 1, 1, 1, 1, 1, 1, 1]\" data-bind-scroll-on-start=\"true\">\n<div id=\"mntl-sc-block_1-0\" class=\"comp mntl-sc-block beauty-sc-block-callout--finalverdict beauty-sc-block-callout mntl-sc-block-callout mntl-block theme-finalverdict\" data-tracking-id=\"mntl-sc-block-callout\" data-tracking-container=\"true\">\n<p id=\"mntl-sc-block-callout-heading_1-0\" class=\"comp mntl-sc-block-callout-heading mntl-text-block\">Key Takeaways<\/p>\n<div id=\"mntl-sc-block-callout-body_1-0\" class=\"comp mntl-sc-block-callout-body mntl-text-block\">\n<ul>\n<li>Hyaluronic acid and retinol can be used together to enhance your skincare routine without causing irritation. <\/li>\n<li>Hyaluronic acid helps mitigate retinol&#8217;s drying effects by increasing skin hydration and improving ingredient absorption. <\/li>\n<li>Apply retinol first, then follow with a hyaluronic acid serum and moisturizer to lock in hydration effectively.<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<p id=\"mntl-sc-block_2-0\" class=\"comp mntl-sc-block beauty-sc-block-html mntl-sc-block-html\"> Hyaluronic acid is a hydrating hero, and retinol is the anti-aging, anti-acne powerhouse, so between the two of them, you&#8217;ve got pretty much everything you need, right? Not so fast&#8230;first, it&#8217;s important to know whether the two can even be paired together.\n<\/p>\n<p id=\"mntl-sc-block_4-0\" class=\"comp mntl-sc-block beauty-sc-block-html mntl-sc-block-html\"> While many of us obsess over the basics\u2014the cleansing, moisturizing, and protecting of the skin\u2014determining how the ingredients you\u2019re using interact is equally as important. To help, we went to board-certified dermatologists Jeremy Fenton, MD, and Ivy DeRosa, MD. Below, they share their expert insights into how hyaluronic acid and retinol work (or don&#8217;t) as a pair.<strong> Keep reading to learn more.<\/strong><\/p>\n<div id=\"mntl-sc-block_6-0\" class=\"comp mntl-sc-block beauty-sc-block-callout--meetourexpert beauty-sc-block-callout mntl-sc-block-callout mntl-block theme-meetourexpert\" data-tracking-id=\"mntl-sc-block-callout\" data-tracking-container=\"true\">\n<p id=\"mntl-sc-block-callout-heading_2-0\" class=\"comp mntl-sc-block-callout-heading mntl-text-block\">Meet the Experts<\/p>\n<div id=\"mntl-sc-block-callout-body_2-0\" class=\"comp mntl-sc-block-callout-body mntl-text-block\">\n<ul>\n<li>\u200b\u200bJeremy Fenton, MD, is a board-certified dermatologist at Schweiger Dermatology Group in New York City.<\/li>\n<li>Ivy DeRosa, MD, is a board-certified medical and cosmetic dermatologist with a small private practice outside of Philadelphia.<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<h2 id=\"mntl-sc-block_7-0\" class=\"comp mntl-sc-block beauty-sc-block-heading mntl-sc-block-heading\"><span class=\"mntl-sc-block-heading__text text-title-300\"> What Is Hyaluronic Acid? <\/span><\/h2>\n<p id=\"mntl-sc-block_8-0\" class=\"comp mntl-sc-block beauty-sc-block-html mntl-sc-block-html\"> Hyaluronic acid is a hydrating ingredient that moisturizes skin, reduces the appearance of wrinkles, replenishes cell moisture, and speeds wound healing. To get more scientific about it, as Dr. DeRosa explains, &#8220;Hyaluronic acid (HA) is a molecule in a class called humectants. Their job is to help retain water in your skin.&#8221; And, as we know, hydration gives skin that dewy, glowy effect we all strive for.\n<\/p>\n<p id=\"mntl-sc-block_10-0\" class=\"comp mntl-sc-block beauty-sc-block-html mntl-sc-block-html\"> Hyaluronic acid &#8220;comes in many different forms over the counter, like serums or lotions, and help to fill the nooks and crannies our skin develops over time due to pollution, sun damage, and the normal aging process,&#8221; Dr. DeRosa says, adding: &#8220;HAs don&#8217;t change the architecture of your skin in the long run, as retinoids do, but they can help for a temporary improvement in the look and feel of your skin.&#8221;\n<\/p>\n<p id=\"mntl-sc-block_12-0\" class=\"comp mntl-sc-block beauty-sc-block-html mntl-sc-block-html\"> It\u2019s generally safe for all skin types and has no known side effects (at least when applied topically).\n<\/p>\n<h2 id=\"mntl-sc-block_14-0\" class=\"comp mntl-sc-block beauty-sc-block-heading mntl-sc-block-heading\"><span class=\"mntl-sc-block-heading__text text-title-300\"> What Is Retinol? <\/span><\/h2>\n<p id=\"mntl-sc-block_15-0\" class=\"comp mntl-sc-block beauty-sc-block-html mntl-sc-block-html\"> If hyaluronic acid is the popular girl who\u2019s nice to everyone, think of retinol as her equally popular but very intimidating best friend. According to Dr. Fenton, retinol is an antioxidant that increases cell turnover, boosts collagen production, and regulates oil production\u2014it\u2019s regularly lauded as a godsend for anyone looking to address texture, acne, or signs of aging. It can also work synergistically with other topicals. &#8220;Retinol may be helpful in combination with other topical treatments because it exfoliates the skin and can allow ingredients to penetrate deeper, making them more effective,&#8221; says Dr. Fenton.\n<\/p>\n<p id=\"mntl-sc-block_17-0\" class=\"comp mntl-sc-block beauty-sc-block-html mntl-sc-block-html\"> But retinol also comes with some serious side effects (both doctors note dryness, peeling, and irritation) and the potential for intense, prolonged purging. Hence the intimidation.\n<\/p>\n<h2 id=\"mntl-sc-block_19-0\" class=\"comp mntl-sc-block beauty-sc-block-heading mntl-sc-block-heading\"><span class=\"mntl-sc-block-heading__text text-title-300\"> Can You Use Hyaluronic Acid and Retinol Together? <\/span><\/h2>\n<p id=\"mntl-sc-block_20-0\" class=\"comp mntl-sc-block beauty-sc-block-html mntl-sc-block-html\"> Much like the girls in our high school analogy, hyaluronic acid and retinol are a match made in heaven. Where retinol is rough, hyaluronic acid is soft; where hyaluronic acid is weak, retinol is strong. Together, they balance each other out without compromising the things that make them unique. It\u2019s exactly what makes the combination one of the most popular across all skincare ingredients.<\/p>\n<div id=\"mntl-sc-block_22-0\" class=\"comp mntl-sc-block beauty-sc-block-callout--tips beauty-sc-block-callout mntl-sc-block-callout mntl-block theme-tips\" data-tracking-id=\"mntl-sc-block-callout\" data-tracking-container=\"true\">\n<p id=\"mntl-sc-block-callout-heading_3-0\" class=\"comp mntl-sc-block-callout-heading mntl-text-block\">Key Takeaways<\/p>\n<div id=\"mntl-sc-block-callout-body_3-0\" class=\"comp mntl-sc-block-callout-body mntl-text-block\">\n<ul>\n<li>Hyaluronic acid and retinol can be used within the same routine without concern for irritation.<\/li>\n<li>Due to its powerful hydrating properties, hyaluronic acid can even help mitigate the side effects of retinol.<\/li>\n<li>When using both ingredients together, apply your retinol first, then follow up with a hyaluronic acid serum.<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<h2 id=\"mntl-sc-block_23-0\" class=\"comp mntl-sc-block beauty-sc-block-heading mntl-sc-block-heading\"><span class=\"mntl-sc-block-heading__text text-title-300\"> Benefits of Using Hyaluronic Acid and Retinol Together <\/span><\/h2>\n<p id=\"mntl-sc-block_24-0\" class=\"comp mntl-sc-block beauty-sc-block-html mntl-sc-block-html\"> As we said, hyaluronic acid and retinol are the ultimate duo. Together, they have a sort of synergistic effect, making it easier to reap the benefits of retinol without suffering any of the usual dryness thanks to the moisture boost from hyaluronic acid.\u00a0\n<\/p>\n<p id=\"mntl-sc-block_26-0\" class=\"comp mntl-sc-block beauty-sc-block-html mntl-sc-block-html\"> Hyaluronic acid helps keep retinol in check, increasing the permeability of the skin. So when combined, the two ingredients can leave your skin clearer, smoother, and more hydrated and moisturized. What more could you ask for?\n<\/p>\n<p id=\"mntl-sc-block_28-0\" class=\"comp mntl-sc-block beauty-sc-block-html mntl-sc-block-html\"> Not to mention it\u2019s a combination you might already be using: many moisturizers contain hyaluronic acid anyway. Likewise, Dr. DeRosa says many high-quality, over-the-counter retinol products are formulated with hydrating and calming ingredients to help mitigate irritation, so there\u2019s a chance your retinol even contains some hyaluronic acid anyway.\n<\/p>\n<h2 id=\"mntl-sc-block_30-0\" class=\"comp mntl-sc-block beauty-sc-block-heading mntl-sc-block-heading\"><span class=\"mntl-sc-block-heading__text text-title-300\"> Potential Side Effects of Using Hyaluronic Acid with Retinol <\/span><\/h2>\n<p id=\"mntl-sc-block_31-0\" class=\"comp mntl-sc-block beauty-sc-block-html mntl-sc-block-html\"> As is the case with all skincare ingredients, there\u2019s always some sort of potential for irritation. That potential is fairly high with retinol and very low with hyaluronic acid.\u00a0So, yes, there is still a chance of irritation but it is a very, very small one\u2014and that irritation would likely be caused not by the <em>combination<\/em> of retinol and hyaluronic acid but by the retinol itself.\n<\/p>\n<h2 id=\"mntl-sc-block_33-0\" class=\"comp mntl-sc-block beauty-sc-block-heading mntl-sc-block-heading\"><span class=\"mntl-sc-block-heading__text text-title-300\"> How to Use Hyaluronic Acid With Retinol <\/span><\/h2>\n<p id=\"mntl-sc-block_34-0\" class=\"comp mntl-sc-block beauty-sc-block-html mntl-sc-block-html\"> Dr. DeRosa provides the following timeline for the application of HA and retinol products: &#8220;If dealing with sensitive or dry skin, a great way to tolerate a retinol is by first cleansing with a gentle wash; no scrubs, toners or physical exfoliants. Then apply a pea-sized amount (that&#8217;s right- just a pea, more is not better) of retinol to the face, and apply a small amount of a hyaluronic acid serum followed by a moisturizer cream. The moisturizer helps to lock in the HA so it can amplify the helpfulness of your moisturizer.&#8221;\n<\/p>\n<p id=\"mntl-sc-block_36-0\" class=\"comp mntl-sc-block beauty-sc-block-html mntl-sc-block-html\"> Try applying a moisturizer or hyaluronic acid in gel form around 30 minutes after applying retinol so that the treatment can dry and soak into the skin before moisturizing. For those with dry or sensitive skin, try using a hyaluronic acid serum prior to retinol. Then, once the retinol has dried, apply a moisturizer.\n<\/p>\n<h2 id=\"mntl-sc-block_38-0\" class=\"comp mntl-sc-block beauty-sc-block-heading mntl-sc-block-heading\"><span class=\"mntl-sc-block-heading__text text-title-300\"> How to Minimize Irritation <\/span><\/h2>\n<p id=\"mntl-sc-block_39-0\" class=\"comp mntl-sc-block beauty-sc-block-html mntl-sc-block-html\"> An important note: the importance of proper application methods when it comes to retinol and hyaluronic acid cannot be overstates. Be sure to give your retinol time to dry and seep into the skin before moving on to the next steps. This will minimize irritation.\n<\/p>\n<h2 id=\"mntl-sc-block_41-0\" class=\"comp mntl-sc-block beauty-sc-block-heading mntl-sc-block-heading\"><span class=\"mntl-sc-block-heading__text text-title-300\"> The Final Takeaway <\/span><\/h2>\n<p id=\"mntl-sc-block_42-0\" class=\"comp mntl-sc-block beauty-sc-block-html mntl-sc-block-html\"> Not only <em>can<\/em> you use hyaluronic acid and retinol together, but both doctors actually <em>encourage<\/em> you to. And they\u2019re not alone: Few other ingredient combinations are as well-regarded as hyaluronic acid and retinol in the skincare community.\n<\/p>\n<p id=\"mntl-sc-block_44-0\" class=\"comp mntl-sc-block beauty-sc-block-html mntl-sc-block-html\"> On their own, hyaluronic acid and retinol are both considered two of the most popular ingredients in anti-aging skincare products. Because hyaluronic acid draws water into the skin while retinol speeds cellular turnover, you can counteract some of retinol\u2019s notorious drying properties while still allowing the ingredient to penetrate the outer layer of the skin. If anything, results are only better when you combine the two. So give the combo a try\u2014you can thank me later.\n<\/p>\n<\/div>\n<div id=\"citation-sources_1-0\" class=\"comp citation-sources mntl-article-sources mntl-expandable-block u-article-styles\" data-scroll-offset=\"70\">\n<div class=\"loc toggle-content\">\n<div id=\"mntl-article-sources__wrapper_1-0\" class=\"comp mntl-article-sources__wrapper mntl-block\" data-click-tracked=\"true\"><span id=\"mntl-article-sources__heading_1-0\" class=\"comp mntl-article-sources__heading mntl-text-block\">Article Sources<\/span><\/div>\n<\/div>\n<div class=\"loc expandable-content\">\n<div id=\"citation-sources__text_1-0\" class=\"comp citation-sources__text mntl-text-block\">Byrdie takes every opportunity to use high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial guidelines to learn more about how we keep our content accurate, reliable and trustworthy.<\/div>\n<div id=\"mntl-article-sources__citation-sources_1-0\" class=\"comp mntl-article-sources__citation-sources mntl-citation-sources mntl-sources\" data-tracking-container=\"true\">\n<ol class=\"mntl-sources__content\">\n<li class=\"mntl-sources__source\" id=\"citation-1\">\n<p>Iaconisi GN, Lunetti P, Gallo N, Cappello AR, Fiermonte G, Dolce V, Capobianco L. Hyaluronic Acid: A Powerful Biomolecule with Wide-Ranging Applications-A Comprehensive Review. Int J Mol Sci. 2023 Jun 18;24(12):10296. doi: 10.3390\/ijms241210296. PMID: 37373443; PMCID: PMC10299688.<\/p>\n<\/li>\n<li class=\"mntl-sources__source\" id=\"citation-2\">\n<p>Mukherjee S, Date A, Patravale V, Korting HC, Roeder A, Weindl G. Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety. Clin Interv Aging. 2006;1(4):327-48. doi: 10.2147\/ciia.2006.1.4.327. PMID: 18046911; PMCID: PMC2699641.<\/p>\n<\/li>\n<li class=\"mntl-sources__source\" id=\"citation-3\">\n<p>Li WH, Wong HK, Serrano J, Randhawa M, Kaur S, Southall MD, Parsa R. Topical stabilized retinol treatment induces the expression of HAS genes and HA production in human skin in vitro and in vivo. Arch Dermatol Res. 2017 May;309(4):275-283. doi: 10.1007\/s00403-017-1723-6. Epub 2017 Feb 28. PMID: 28247017.<\/p>\n<\/li>\n<\/ol>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"loc article-post-content\">\n<div id=\"beauty-breadcrumbs--chips_1-0\" class=\"comp beauty-breadcrumbs--chips mntl-universal-breadcrumbs--chips mntl-block\">\n<div id=\"mntl-breadcrumbs__read-more_1-0\" class=\"comp mntl-breadcrumbs__read-more mntl-text-block text-title-100\">Read more:<\/div>\n<ul id=\"mntl-universal-breadcrumbs_1-0\" class=\"comp mntl-universal-breadcrumbs mntl-block text-label-300 breadcrumbs\" data-tracking-container=\"true\">\n<li id=\"mntl-breadcrumbs__item_1-0\" class=\"comp mntl-breadcrumbs__item mntl-block\"><span class=\"link__wrapper\">Skin<\/span><\/li>\n<li id=\"mntl-breadcrumbs__item_2-0\" class=\"comp mntl-breadcrumbs__item mntl-block\"><span class=\"link__wrapper\">Face Care<\/span><\/li>\n<\/ul>\n<\/div>\n<\/div>\n<\/article>\n<div id=\"recirc_1-0\" class=\"comp recirc mntl-block\" data-tracking-container=\"true\">\n<h2 id=\"recirc__heading_1-0\" 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title=\"byr-facial-self-tanners-tout-recirc-a597c5bf71fe4b29902c81c9e814e9aa-4\"><\/div>\n<\/div>\n<\/div>\n<div class=\"card__content \"><span class=\"card__title\"><span class=\"card__title-text \">The 6 Best Tester-Approved Facial Self-Tanners for a Year-Round Tropical Glow<\/span><\/span><\/div>\n<\/li>\n<li id=\"card-list__item_12-0\" class=\"comp card-list__item mntl-block \">\n<div class=\"loc card__top\">\n<div class=\"card__media mntl-image card__media universal-image__container\">\n<div class=\"img-placeholder\"><img loading=\"lazy\" decoding=\"async\" width=\"300\" height=\"240\" alt=\"A person holding a jar or Peter Thomas Roth Pumpkin Enzyme Mask Enzymatic Dermal Resurfacer and a person with a face mask on\" class=\"lazyload card__img universal-image__image\" src=\"https:\/\/analyse.optim.biz\/wp-content\/uploads\/2026\/02\/byr-best-face-masks-recirc-5275fa5cb63c497cbb4cd2b07d795369-5.webp\" title=\"byr-best-face-masks-recirc-5275fa5cb63c497cbb4cd2b07d795369-5\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/analyse.optim.biz\/wp-content\/uploads\/2026\/02\/byr-best-face-masks-recirc-5275fa5cb63c497cbb4cd2b07d795369-5.webp\" width=\"300\" height=\"240\" class=\"img--noscript card__img universal-image__image\" alt=\"A person holding a jar or Peter Thomas Roth Pumpkin Enzyme Mask Enzymatic Dermal Resurfacer and a person with a face mask on\" title=\"byr-best-face-masks-recirc-5275fa5cb63c497cbb4cd2b07d795369-5\"><\/div>\n<\/div>\n<\/div>\n<div class=\"card__content \"><span class=\"card__title\"><span class=\"card__title-text \">The 11 Best Face Masks for Smooth, Hydrated Skin, Approved by Testers<\/span><\/span><\/div>\n<\/li>\n<li id=\"card-list__item_13-0\" class=\"comp card-list__item mntl-block \">\n<div class=\"loc card__top\">\n<div class=\"card__media mntl-image card__media universal-image__container\">\n<div class=\"img-placeholder\"><img loading=\"lazy\" decoding=\"async\" width=\"300\" height=\"240\" alt=\"Retinol Eye Cream Featuring The Before and After Shots of Person Using Murad Retinal Resculpt Eye Treatment\" class=\"lazyload card__img universal-image__image\" src=\"https:\/\/analyse.optim.biz\/wp-content\/uploads\/2026\/02\/byr-retinol-eye-cream-tout-recirc-a9f335a911be4051a849d45082d44a3e-4.webp\" title=\"byr-retinol-eye-cream-tout-recirc-a9f335a911be4051a849d45082d44a3e-4\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/analyse.optim.biz\/wp-content\/uploads\/2026\/02\/byr-retinol-eye-cream-tout-recirc-a9f335a911be4051a849d45082d44a3e-4.webp\" width=\"300\" height=\"240\" class=\"img--noscript card__img universal-image__image\" alt=\"Retinol Eye Cream Featuring The Before and After Shots of Person Using Murad Retinal Resculpt Eye Treatment\" title=\"byr-retinol-eye-cream-tout-recirc-a9f335a911be4051a849d45082d44a3e-4\"><\/div>\n<\/div>\n<\/div>\n<div class=\"card__content \"><span class=\"card__title\"><span class=\"card__title-text \">The 7 Best Retinol Eye Creams That Tighten, Firm, and Smooth Skin<\/span><\/span><\/div>\n<\/li>\n<li id=\"card-list__item_14-0\" class=\"comp card-list__item mntl-block \">\n<div class=\"loc card__top\">\n<div class=\"card__media mntl-image card__media universal-image__container\">\n<div class=\"img-placeholder\"><img loading=\"lazy\" decoding=\"async\" width=\"300\" height=\"240\" alt=\"Closeup of a person partially covered in a textured fabric gazing at the camera\" class=\"lazyload card__img universal-image__image\" src=\"https:\/\/analyse.optim.biz\/wp-content\/uploads\/2026\/02\/micellarwater-2-9cb1e8742e714758902fd0832a7de649-3.webp\" title=\"micellarwater-2-9cb1e8742e714758902fd0832a7de649-3\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/analyse.optim.biz\/wp-content\/uploads\/2026\/02\/micellarwater-2-9cb1e8742e714758902fd0832a7de649-3.webp\" width=\"300\" height=\"240\" class=\"img--noscript card__img universal-image__image\" alt=\"Closeup of a person partially covered in a textured fabric gazing at the camera\" title=\"micellarwater-2-9cb1e8742e714758902fd0832a7de649-3\"><\/div>\n<\/div>\n<\/div>\n<div class=\"card__content \"><span class=\"card__title\"><span class=\"card__title-text \">Micellar Water Is a Sensitive-Skin Staple for a Reason\u2014Here&#8217;s the Right Way to Use It, According to Derms<\/span><\/span><\/div>\n<\/li>\n<li id=\"card-list__item_15-0\" class=\"comp card-list__item mntl-block \">\n<div class=\"loc card__top\">\n<div class=\"card__media mntl-image card__media universal-image__container\">\n<div class=\"img-placeholder\"><img loading=\"lazy\" decoding=\"async\" width=\"300\" height=\"240\" alt=\"Two people demonstrating the use of gua sha tools on their faces\" class=\"lazyload card__img universal-image__image\" src=\"https:\/\/analyse.optim.biz\/wp-content\/uploads\/2026\/02\/byr-best-gua-sha-tools-tout-recirc-0aba5b2ebad9470eba9989cb2fc8b6d9-5.webp\" title=\"byr-best-gua-sha-tools-tout-recirc-0aba5b2ebad9470eba9989cb2fc8b6d9-5\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/analyse.optim.biz\/wp-content\/uploads\/2026\/02\/byr-best-gua-sha-tools-tout-recirc-0aba5b2ebad9470eba9989cb2fc8b6d9-5.webp\" width=\"300\" height=\"240\" class=\"img--noscript card__img universal-image__image\" alt=\"Two people demonstrating the use of gua sha tools on their faces\" title=\"byr-best-gua-sha-tools-tout-recirc-0aba5b2ebad9470eba9989cb2fc8b6d9-5\"><\/div>\n<\/div>\n<\/div>\n<div class=\"card__content \"><span class=\"card__title\"><span class=\"card__title-text \">The 7 Best Gua Sha Tools for Sculpted, Glowing Skin\u2014and We Can Show You the Proof<\/span><\/span><\/div>\n<\/li>\n<li id=\"card-list__item_16-0\" class=\"comp card-list__item mntl-block \">\n<div class=\"loc card__top\">\n<div class=\"card__media mntl-image card__media universal-image__container\">\n<div class=\"img-placeholder\"><img loading=\"lazy\" decoding=\"async\" width=\"300\" height=\"240\" alt=\"A closeup of a lip gloss applicator and tube\" class=\"lazyload card__img universal-image__image\" src=\"https:\/\/analyse.optim.biz\/wp-content\/uploads\/2026\/02\/byr_lipglosslostplot_leadrecirc-d984294b76444320ba34cc346a534e4b-3.webp\" title=\"byr_lipglosslostplot_leadrecirc-d984294b76444320ba34cc346a534e4b-3\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/analyse.optim.biz\/wp-content\/uploads\/2026\/02\/byr_lipglosslostplot_leadrecirc-d984294b76444320ba34cc346a534e4b-3.webp\" width=\"300\" height=\"240\" class=\"img--noscript card__img universal-image__image\" alt=\"A closeup of a lip gloss applicator and tube\" title=\"byr_lipglosslostplot_leadrecirc-d984294b76444320ba34cc346a534e4b-3\"><\/div>\n<\/div>\n<\/div>\n<div class=\"card__content \"><span class=\"card__title\"><span class=\"card__title-text \">We&#8217;ve Lost the Plot on Lip Balm<\/span><\/span><\/div>\n<\/li>\n<\/ul>\n<\/div>\n<p><\/main><\/p>\n<article id=\"beauty-article--sc_1-0\" class=\"comp beauty-article--sc beauty-article mntl-article mntl-article--three-column sc-ad-container\" data-tracking-container=\"true\">\n<div class=\"loc article-header\">\n<div id=\"article-header_1-0\" class=\"comp article-header mntl-block article-top\">\n<h1 id=\"article-heading_1-0\" class=\"comp article-heading mntl-text-block\">Is It Safe to Use Hyaluronic Acid With Retinol? Dermatologists Weigh In<\/h1>\n<p id=\"article-subheading_1-0\" class=\"comp article-subheading mntl-text-block\">Hint: You&#8217;re probably already mixing them.<\/p>\n<div id=\"article-meta_1-0\" class=\"comp article-meta mntl-article-meta mntl-block\" data-tracking-container=\"true\">\n<div id=\"bylines_1-0\" class=\"comp bylines beauty-bylines mntl-bylines\" data-tracking-container=\"true\">\n<div id=\"mntl-bylines__group_1-0\" class=\"comp mntl-bylines__group mntl-block mntl-bylines__group--author\">\n<div id=\"mntl-bylines__item_1-0\" class=\"comp mntl-bylines__item mntl-attribution__item mntl-attribution__item--has-date\"><span class=\"mntl-attribution__item-descriptor\">By<\/span><\/p>\n<div data-tooltip=\"Dani is New York-based beauty writer and editor. Her work has been featured in Allure, Elle, InStyle, Well + Good, and more.\" data-inline-tooltip=\"true\"> Dani Hardman<\/p>\n<div id=\"mntl-author-tooltip_1-0\" class=\"comp mntl-author-tooltip mntl-tooltip mntl-group\">\n<div class=\"mntl-author-tooltip__top \">\n<div class=\"mntl-author-tooltip__image-wrapper\">\n<div class=\"img-placeholder\"><img loading=\"lazy\" decoding=\"async\" width=\"200\" height=\"200\" alt=\"Danielle Cohen\" class=\"lazyload mntl-author-tooltip__image mntl-image universal-image__image\" src=\"https:\/\/analyse.optim.biz\/wp-content\/uploads\/2026\/02\/byrdieimagesize-130b5be39471413aa98b61be592acaa3-5.webp\" title=\"byrdieimagesize-130b5be39471413aa98b61be592acaa3-5\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/analyse.optim.biz\/wp-content\/uploads\/2026\/02\/byrdieimagesize-130b5be39471413aa98b61be592acaa3-5.webp\" width=\"200\" height=\"200\" class=\"img--noscript mntl-author-tooltip__image mntl-image universal-image__image\" alt=\"Danielle Cohen\" title=\"byrdieimagesize-130b5be39471413aa98b61be592acaa3-5\"><\/div>\n<\/div>\n<div id=\"mntl-author-tooltip__name_1-0\" class=\"comp mntl-author-tooltip__name mntl-attribution__item \">\nDani Hardman\n<\/div>\n<div id=\"mntl-author-tooltip__social-nav_1-0\" class=\"comp mntl-author-tooltip__social-nav beauty-social-nav mntl-social-nav social-nav--tooltip\" data-tracking-container=\"true\">\n<ul class=\"social-nav__list\">\n<li class=\"social-nav__item social-nav__item--instagram\">\n<li class=\"social-nav__item social-nav__item--linkedin\"><\/ul>\n<\/div>\n<div class=\"mntl-author-tooltip__bio\">\nDani is New York-based beauty writer and editor. Her work has been featured in Allure, Elle, InStyle, Well + Good, and more.\n<\/div>\n<\/div>\n<div class=\"mntl-author-tooltip__bottom\">\nByrdie&#8217;s Editorial Guidelines\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"mntl-attribution__item-date\">Published on January 19, 2026 08:15AM<\/div>\n<\/div>\n<div id=\"mntl-bylines__group_2-0\" class=\"comp mntl-bylines__group mntl-block mntl-bylines__group--beauty_wellness_reviewer\">\n<div id=\"mntl-bylines__item_2-0\" class=\"comp mntl-bylines__item mntl-attribution__item \"><span class=\"mntl-attribution__item-descriptor\">Reviewed by<\/span><\/p>\n<div data-tooltip=\"Julia A. Siegel, MD is a board-certified dermatologist based in Boston, Massachusetts. She is a member of the American Academy of Dermatology and has authored several peer-reviewed journal articles and book chapters.\u00a0\" data-inline-tooltip=\"true\"> Julia A. Siegel, MD<\/p>\n<div id=\"mntl-author-tooltip_2-0\" class=\"comp mntl-author-tooltip mntl-tooltip mntl-group\">\n<div class=\"mntl-author-tooltip__top \">\n<div class=\"mntl-author-tooltip__image-wrapper\">\n<div class=\"img-placeholder\"><img loading=\"lazy\" decoding=\"async\" width=\"200\" height=\"200\" alt=\"Julia Siegel\" class=\"lazyload mntl-author-tooltip__image mntl-image universal-image__image\" src=\"https:\/\/analyse.optim.biz\/wp-content\/uploads\/2026\/02\/juliasiegel-e3dee3e76304428b9357e4fe8da1a50b-12.webp\" title=\"juliasiegel-e3dee3e76304428b9357e4fe8da1a50b-12\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/analyse.optim.biz\/wp-content\/uploads\/2026\/02\/juliasiegel-e3dee3e76304428b9357e4fe8da1a50b-12.webp\" width=\"200\" height=\"200\" class=\"img--noscript mntl-author-tooltip__image mntl-image universal-image__image\" alt=\"Julia Siegel\" title=\"juliasiegel-e3dee3e76304428b9357e4fe8da1a50b-12\"><\/div>\n<\/div>\n<div id=\"mntl-author-tooltip__name_2-0\" class=\"comp mntl-author-tooltip__name mntl-attribution__item \"><span class=\"mntl-attribution__item-descriptor\">Reviewed by<\/span><br \/>\nJulia A. Siegel, MD\n<\/div>\n<div class=\"mntl-author-tooltip__bio\">\nJulia A. Siegel, MD is a board-certified dermatologist based in Boston, Massachusetts. She is a member of the American Academy of Dermatology and has authored several peer-reviewed journal articles and book chapters.\u00a0\n<\/div>\n<\/div>\n<div class=\"mntl-author-tooltip__bottom\">\nAbout Byrdie&#8217;s Beauty &amp; Wellness Board\n<\/div>\n<\/div>\n<\/div>\n<div class=\"mntl-attribution__item-postscript\">Board-Certified Dermatologist<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"loc article-left-rail\">\n<div id=\"beauty-sticky-toc_1-0\" class=\"comp beauty-sticky-toc mntl-block js-sticky-container sticky-toc__wrapper\">\n<div id=\"sticky-toc_1-0\" class=\"comp sticky-toc mntl-universal-sticky-toc mntl-sticky-toc mntl-block sticky-toc-widget\" data-desktop-bp=\"70em\">\n<div id=\"toc-wrapper_1-0\" class=\"comp toc-wrapper mntl-toc mntl-block\" data-chop-mobile=\"true\" data-offset=\"60\" data-tracking-container=\"true\">\n<div id=\"mntl-toc__inner_1-0\" class=\"comp mntl-toc__inner mntl-block\">\n<div id=\"mntl-toc__heading_1-0\" class=\"comp mntl-toc__heading mntl-block js-toc-toggle\"><span id=\"mntl-toc__heading-text_1-0\" class=\"comp mntl-toc__heading-text mntl-text-block\">In This Article<\/span><\/p>\n<div id=\"mntl-toc-toggle_1-0\" class=\"comp mntl-toc-toggle mntl-block\">\n<div id=\"mntl-toc-toggle__btn_1-0\" class=\"comp mntl-toc-toggle__btn mntl-text-block js-mntl-toc-toggle text-label-300\" data-click-tracked=\"true\" data-collapsed-text=\"View All\" data-expanded-text=\"View Less\">View All<\/div>\n<\/div>\n<\/div>\n<div id=\"mntl-toc__mobile-toggle_1-0\" class=\"comp mntl-toc__mobile-toggle mntl-block js-sticky-toggle\"><span id=\"mntl-toc__heading-text_2-0\" class=\"comp mntl-toc__heading-text mntl-text-block\">In This Article<\/span><\/div>\n<ul id=\"mntl-toc__list_1-0\" class=\"comp mntl-toc__list mntl-toc__list-heading expert-content text-utility-300\">\n<li id=\"mntl-toc__list-item_1-0\" class=\"comp mntl-toc__list-item mntl-block\">\n<div id=\"mntl-toc__list-item-heading_1-0\" class=\"comp mntl-toc__list-item-heading mntl-block\"><span class=\"link__wrapper\">What Is Hyaluronic Acid?<\/span><\/div>\n<\/li>\n<li id=\"mntl-toc__list-item_2-0\" class=\"comp mntl-toc__list-item mntl-block\">\n<div id=\"mntl-toc__list-item-heading_2-0\" class=\"comp mntl-toc__list-item-heading mntl-block\"><span class=\"link__wrapper\">What Is Retinol?<\/span><\/div>\n<\/li>\n<li id=\"mntl-toc__list-item_3-0\" class=\"comp mntl-toc__list-item mntl-block\">\n<div id=\"mntl-toc__list-item-heading_3-0\" class=\"comp mntl-toc__list-item-heading mntl-block\"><span class=\"link__wrapper\">Can You Use Them Together?<\/span><\/div>\n<\/li>\n<li id=\"mntl-toc__list-item_4-0\" class=\"comp mntl-toc__list-item mntl-block\">\n<div id=\"mntl-toc__list-item-heading_4-0\" class=\"comp mntl-toc__list-item-heading mntl-block\"><span class=\"link__wrapper\">Benefits<\/span><\/div>\n<\/li>\n<li id=\"mntl-toc__list-item_5-0\" class=\"comp mntl-toc__list-item mntl-block\">\n<div id=\"mntl-toc__list-item-heading_5-0\" class=\"comp mntl-toc__list-item-heading mntl-block\"><span class=\"link__wrapper\">Side Effects<\/span><\/div>\n<\/li>\n<li id=\"mntl-toc__list-item_6-0\" class=\"comp mntl-toc__list-item mntl-block\">\n<div id=\"mntl-toc__list-item-heading_6-0\" class=\"comp mntl-toc__list-item-heading mntl-block\"><span class=\"link__wrapper\">How to Use Together<\/span><\/div>\n<\/li>\n<li id=\"mntl-toc__list-item_7-0\" class=\"comp mntl-toc__list-item mntl-block\">\n<div id=\"mntl-toc__list-item-heading_7-0\" class=\"comp mntl-toc__list-item-heading mntl-block\"><span class=\"link__wrapper\">Minimize Irritation<\/span><\/div>\n<\/li>\n<li id=\"mntl-toc__list-item_8-0\" class=\"comp mntl-toc__list-item mntl-block\">\n<div id=\"mntl-toc__list-item-heading_8-0\" class=\"comp mntl-toc__list-item-heading mntl-block\"><span class=\"link__wrapper\">The Final Takeaway<\/span><\/div>\n<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"loc article-content\">\n<div id=\"article__broad-video-jw_1-0\" class=\"comp article__broad-video-jw mntl-jwplayer-broad mntl-block is-hidden\" data-pixel-depth=\"100\">\n<div id=\"mntl-jwplayer-broad__title_1-0\" class=\"comp mntl-jwplayer-broad__title mntl-block\"><button id=\"mntl-jwplayer-broad__title-icon--close_1-0\" class=\"comp mntl-jwplayer-broad__title-icon--close mntl-block text-label-100\" data-click-tracked=\"false\"><span id=\"mntl-text-block_2-0\" class=\"comp mntl-text-block\">Close<\/span><\/button><\/div>\n<\/div>\n<div id=\"mntl-block_2-0\" class=\"comp mntl-block article__body right-rail\">\n<figure id=\"mntl-universal-primary-image_1-0\" class=\"comp mntl-universal-primary-image primary-image\" data-tracking-container=\"true\">\n<div class=\"primary-image__media\">\n<div class=\"img-placeholder\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/analyse.optim.biz\/wp-content\/uploads\/2026\/02\/skincare-2-a9b87ad2a2b142379b8bf91d791cc5d1-4.webp\" width=\"1280\" height=\"960\" alt=\"A closeup of an open skincare tube with product visible at the top\" class=\" primary-image__image mntl-primary-image--blurry\" title=\"skincare-2-a9b87ad2a2b142379b8bf91d791cc5d1-4\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/analyse.optim.biz\/wp-content\/uploads\/2026\/02\/skincare-2-a9b87ad2a2b142379b8bf91d791cc5d1-4.webp\" width=\"1280\" height=\"960\" class=\"loaded primary-img--noscript primary-image__image mntl-primary-image--blurry\" alt=\"A closeup of an open skincare tube with product visible at the top\" title=\"skincare-2-a9b87ad2a2b142379b8bf91d791cc5d1-4\"><\/div>\n<\/div><figcaption id=\"primary-image__figcap_1-0\" class=\"comp primary-image__figcap mntl-figure-caption figure-article-caption\"><span class=\"figure-article-caption-owner\"><\/p>\n<p>Death to Stock<\/p>\n<p><\/span><\/figcaption><\/figure>\n<div id=\"mntl-sc-page_1-0\" class=\"comp mntl-sc-page mntl-block\" data-sc-sticky-offset=\"125\" data-sc-ad-label-height=\"16\" data-sc-ad-track-spacing=\"100\" data-sc-min-track-height=\"250\" data-sc-max-track-height=\"600\" data-sc-breakpoint=\"50em\" data-sc-load-immediate=\"5\" data-sc-content-positions=\"[1, 1250, 1, 1, 1, 1, 1, 1, 1]\" data-bind-scroll-on-start=\"true\">\n<div id=\"mntl-sc-block_1-0\" class=\"comp mntl-sc-block beauty-sc-block-callout--finalverdict beauty-sc-block-callout mntl-sc-block-callout mntl-block theme-finalverdict\" data-tracking-id=\"mntl-sc-block-callout\" data-tracking-container=\"true\">\n<p id=\"mntl-sc-block-callout-heading_1-0\" class=\"comp mntl-sc-block-callout-heading mntl-text-block\">Key Takeaways<\/p>\n<div id=\"mntl-sc-block-callout-body_1-0\" class=\"comp mntl-sc-block-callout-body mntl-text-block\">\n<ul>\n<li>Hyaluronic acid and retinol can be used together to enhance your skincare routine without causing irritation. <\/li>\n<li>Hyaluronic acid helps mitigate retinol&#8217;s drying effects by increasing skin hydration and improving ingredient absorption. <\/li>\n<li>Apply retinol first, then follow with a hyaluronic acid serum and moisturizer to lock in hydration effectively.<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<p id=\"mntl-sc-block_2-0\" class=\"comp mntl-sc-block beauty-sc-block-html mntl-sc-block-html\"> Hyaluronic acid is a hydrating hero, and retinol is the anti-aging, anti-acne powerhouse, so between the two of them, you&#8217;ve got pretty much everything you need, right? Not so fast&#8230;first, it&#8217;s important to know whether the two can even be paired together.\n<\/p>\n<p id=\"mntl-sc-block_4-0\" class=\"comp mntl-sc-block beauty-sc-block-html mntl-sc-block-html\"> While many of us obsess over the basics\u2014the cleansing, moisturizing, and protecting of the skin\u2014determining how the ingredients you\u2019re using interact is equally as important. To help, we went to board-certified dermatologists Jeremy Fenton, MD, and Ivy DeRosa, MD. Below, they share their expert insights into how hyaluronic acid and retinol work (or don&#8217;t) as a pair.<strong> Keep reading to learn more.<\/strong><\/p>\n<div id=\"mntl-sc-block_6-0\" class=\"comp mntl-sc-block beauty-sc-block-callout--meetourexpert beauty-sc-block-callout mntl-sc-block-callout mntl-block theme-meetourexpert\" data-tracking-id=\"mntl-sc-block-callout\" data-tracking-container=\"true\">\n<p id=\"mntl-sc-block-callout-heading_2-0\" class=\"comp mntl-sc-block-callout-heading mntl-text-block\">Meet the Experts<\/p>\n<div id=\"mntl-sc-block-callout-body_2-0\" class=\"comp mntl-sc-block-callout-body mntl-text-block\">\n<ul>\n<li>\u200b\u200bJeremy Fenton, MD, is a board-certified dermatologist at Schweiger Dermatology Group in New York City.<\/li>\n<li>Ivy DeRosa, MD, is a board-certified medical and cosmetic dermatologist with a small private practice outside of Philadelphia.<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<h2 id=\"mntl-sc-block_7-0\" class=\"comp mntl-sc-block beauty-sc-block-heading mntl-sc-block-heading\"><span class=\"mntl-sc-block-heading__text text-title-300\"> What Is Hyaluronic Acid? <\/span><\/h2>\n<p id=\"mntl-sc-block_8-0\" class=\"comp mntl-sc-block beauty-sc-block-html mntl-sc-block-html\"> Hyaluronic acid is a hydrating ingredient that moisturizes skin, reduces the appearance of wrinkles, replenishes cell moisture, and speeds wound healing. To get more scientific about it, as Dr. DeRosa explains, &#8220;Hyaluronic acid (HA) is a molecule in a class called humectants. Their job is to help retain water in your skin.&#8221; And, as we know, hydration gives skin that dewy, glowy effect we all strive for.\n<\/p>\n<p id=\"mntl-sc-block_10-0\" class=\"comp mntl-sc-block beauty-sc-block-html mntl-sc-block-html\"> Hyaluronic acid &#8220;comes in many different forms over the counter, like serums or lotions, and help to fill the nooks and crannies our skin develops over time due to pollution, sun damage, and the normal aging process,&#8221; Dr. DeRosa says, adding: &#8220;HAs don&#8217;t change the architecture of your skin in the long run, as retinoids do, but they can help for a temporary improvement in the look and feel of your skin.&#8221;\n<\/p>\n<p id=\"mntl-sc-block_12-0\" class=\"comp mntl-sc-block beauty-sc-block-html mntl-sc-block-html\"> It\u2019s generally safe for all skin types and has no known side effects (at least when applied topically).\n<\/p>\n<h2 id=\"mntl-sc-block_14-0\" class=\"comp mntl-sc-block beauty-sc-block-heading mntl-sc-block-heading\"><span class=\"mntl-sc-block-heading__text text-title-300\"> What Is Retinol? <\/span><\/h2>\n<p id=\"mntl-sc-block_15-0\" class=\"comp mntl-sc-block beauty-sc-block-html mntl-sc-block-html\"> If hyaluronic acid is the popular girl who\u2019s nice to everyone, think of retinol as her equally popular but very intimidating best friend. According to Dr. Fenton, retinol is an antioxidant that increases cell turnover, boosts collagen production, and regulates oil production\u2014it\u2019s regularly lauded as a godsend for anyone looking to address texture, acne, or signs of aging. It can also work synergistically with other topicals. &#8220;Retinol may be helpful in combination with other topical treatments because it exfoliates the skin and can allow ingredients to penetrate deeper, making them more effective,&#8221; says Dr. Fenton.\n<\/p>\n<p id=\"mntl-sc-block_17-0\" class=\"comp mntl-sc-block beauty-sc-block-html mntl-sc-block-html\"> But retinol also comes with some serious side effects (both doctors note dryness, peeling, and irritation) and the potential for intense, prolonged purging. Hence the intimidation.\n<\/p>\n<h2 id=\"mntl-sc-block_19-0\" class=\"comp mntl-sc-block beauty-sc-block-heading mntl-sc-block-heading\"><span class=\"mntl-sc-block-heading__text text-title-300\"> Can You Use Hyaluronic Acid and Retinol Together? <\/span><\/h2>\n<p id=\"mntl-sc-block_20-0\" class=\"comp mntl-sc-block beauty-sc-block-html mntl-sc-block-html\"> Much like the girls in our high school analogy, hyaluronic acid and retinol are a match made in heaven. Where retinol is rough, hyaluronic acid is soft; where hyaluronic acid is weak, retinol is strong. Together, they balance each other out without compromising the things that make them unique. It\u2019s exactly what makes the combination one of the most popular across all skincare ingredients.<\/p>\n<div id=\"mntl-sc-block_22-0\" class=\"comp mntl-sc-block beauty-sc-block-callout--tips beauty-sc-block-callout mntl-sc-block-callout mntl-block theme-tips\" data-tracking-id=\"mntl-sc-block-callout\" data-tracking-container=\"true\">\n<p id=\"mntl-sc-block-callout-heading_3-0\" class=\"comp mntl-sc-block-callout-heading mntl-text-block\">Key Takeaways<\/p>\n<div id=\"mntl-sc-block-callout-body_3-0\" class=\"comp mntl-sc-block-callout-body mntl-text-block\">\n<ul>\n<li>Hyaluronic acid and retinol can be used within the same routine without concern for irritation.<\/li>\n<li>Due to its powerful hydrating properties, hyaluronic acid can even help mitigate the side effects of retinol.<\/li>\n<li>When using both ingredients together, apply your retinol first, then follow up with a hyaluronic acid serum.<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<h2 id=\"mntl-sc-block_23-0\" class=\"comp mntl-sc-block beauty-sc-block-heading mntl-sc-block-heading\"><span class=\"mntl-sc-block-heading__text text-title-300\"> Benefits of Using Hyaluronic Acid and Retinol Together <\/span><\/h2>\n<p id=\"mntl-sc-block_24-0\" class=\"comp mntl-sc-block beauty-sc-block-html mntl-sc-block-html\"> As we said, hyaluronic acid and retinol are the ultimate duo. Together, they have a sort of synergistic effect, making it easier to reap the benefits of retinol without suffering any of the usual dryness thanks to the moisture boost from hyaluronic acid.\u00a0\n<\/p>\n<p id=\"mntl-sc-block_26-0\" class=\"comp mntl-sc-block beauty-sc-block-html mntl-sc-block-html\"> Hyaluronic acid helps keep retinol in check, increasing the permeability of the skin. So when combined, the two ingredients can leave your skin clearer, smoother, and more hydrated and moisturized. What more could you ask for?\n<\/p>\n<p id=\"mntl-sc-block_28-0\" class=\"comp mntl-sc-block beauty-sc-block-html mntl-sc-block-html\"> Not to mention it\u2019s a combination you might already be using: many moisturizers contain hyaluronic acid anyway. Likewise, Dr. DeRosa says many high-quality, over-the-counter retinol products are formulated with hydrating and calming ingredients to help mitigate irritation, so there\u2019s a chance your retinol even contains some hyaluronic acid anyway.\n<\/p>\n<h2 id=\"mntl-sc-block_30-0\" class=\"comp mntl-sc-block beauty-sc-block-heading mntl-sc-block-heading\"><span class=\"mntl-sc-block-heading__text text-title-300\"> Potential Side Effects of Using Hyaluronic Acid with Retinol <\/span><\/h2>\n<p id=\"mntl-sc-block_31-0\" class=\"comp mntl-sc-block beauty-sc-block-html mntl-sc-block-html\"> As is the case with all skincare ingredients, there\u2019s always some sort of potential for irritation. That potential is fairly high with retinol and very low with hyaluronic acid.\u00a0So, yes, there is still a chance of irritation but it is a very, very small one\u2014and that irritation would likely be caused not by the <em>combination<\/em> of retinol and hyaluronic acid but by the retinol itself.\n<\/p>\n<h2 id=\"mntl-sc-block_33-0\" class=\"comp mntl-sc-block beauty-sc-block-heading mntl-sc-block-heading\"><span class=\"mntl-sc-block-heading__text text-title-300\"> How to Use Hyaluronic Acid With Retinol <\/span><\/h2>\n<p id=\"mntl-sc-block_34-0\" class=\"comp mntl-sc-block beauty-sc-block-html mntl-sc-block-html\"> Dr. DeRosa provides the following timeline for the application of HA and retinol products: &#8220;If dealing with sensitive or dry skin, a great way to tolerate a retinol is by first cleansing with a gentle wash; no scrubs, toners or physical exfoliants. Then apply a pea-sized amount (that&#8217;s right- just a pea, more is not better) of retinol to the face, and apply a small amount of a hyaluronic acid serum followed by a moisturizer cream. The moisturizer helps to lock in the HA so it can amplify the helpfulness of your moisturizer.&#8221;\n<\/p>\n<p id=\"mntl-sc-block_36-0\" class=\"comp mntl-sc-block beauty-sc-block-html mntl-sc-block-html\"> Try applying a moisturizer or hyaluronic acid in gel form around 30 minutes after applying retinol so that the treatment can dry and soak into the skin before moisturizing. For those with dry or sensitive skin, try using a hyaluronic acid serum prior to retinol. Then, once the retinol has dried, apply a moisturizer.\n<\/p>\n<h2 id=\"mntl-sc-block_38-0\" class=\"comp mntl-sc-block beauty-sc-block-heading mntl-sc-block-heading\"><span class=\"mntl-sc-block-heading__text text-title-300\"> How to Minimize Irritation <\/span><\/h2>\n<p id=\"mntl-sc-block_39-0\" class=\"comp mntl-sc-block beauty-sc-block-html mntl-sc-block-html\"> An important note: the importance of proper application methods when it comes to retinol and hyaluronic acid cannot be overstates. Be sure to give your retinol time to dry and seep into the skin before moving on to the next steps. This will minimize irritation.\n<\/p>\n<h2 id=\"mntl-sc-block_41-0\" class=\"comp mntl-sc-block beauty-sc-block-heading mntl-sc-block-heading\"><span class=\"mntl-sc-block-heading__text text-title-300\"> The Final Takeaway <\/span><\/h2>\n<p id=\"mntl-sc-block_42-0\" class=\"comp mntl-sc-block beauty-sc-block-html mntl-sc-block-html\"> Not only <em>can<\/em> you use hyaluronic acid and retinol together, but both doctors actually <em>encourage<\/em> you to. And they\u2019re not alone: Few other ingredient combinations are as well-regarded as hyaluronic acid and retinol in the skincare community.\n<\/p>\n<p id=\"mntl-sc-block_44-0\" class=\"comp mntl-sc-block beauty-sc-block-html mntl-sc-block-html\"> On their own, hyaluronic acid and retinol are both considered two of the most popular ingredients in anti-aging skincare products. Because hyaluronic acid draws water into the skin while retinol speeds cellular turnover, you can counteract some of retinol\u2019s notorious drying properties while still allowing the ingredient to penetrate the outer layer of the skin. If anything, results are only better when you combine the two. So give the combo a try\u2014you can thank me later.\n<\/p>\n<\/div>\n<div id=\"citation-sources_1-0\" class=\"comp citation-sources mntl-article-sources mntl-expandable-block u-article-styles\" data-scroll-offset=\"70\">\n<div class=\"loc toggle-content\">\n<div id=\"mntl-article-sources__wrapper_1-0\" class=\"comp mntl-article-sources__wrapper mntl-block\" data-click-tracked=\"true\"><span id=\"mntl-article-sources__heading_1-0\" class=\"comp mntl-article-sources__heading mntl-text-block\">Article Sources<\/span><\/div>\n<\/div>\n<div class=\"loc expandable-content\">\n<div id=\"citation-sources__text_1-0\" class=\"comp citation-sources__text mntl-text-block\">Byrdie takes every opportunity to use high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial guidelines to learn more about how we keep our content accurate, reliable and trustworthy.<\/div>\n<div id=\"mntl-article-sources__citation-sources_1-0\" class=\"comp mntl-article-sources__citation-sources mntl-citation-sources mntl-sources\" data-tracking-container=\"true\">\n<ol class=\"mntl-sources__content\">\n<li class=\"mntl-sources__source\" id=\"citation-1\">\n<p>Iaconisi GN, Lunetti P, Gallo N, Cappello AR, Fiermonte G, Dolce V, Capobianco L. Hyaluronic Acid: A Powerful Biomolecule with Wide-Ranging Applications-A Comprehensive Review. Int J Mol Sci. 2023 Jun 18;24(12):10296. doi: 10.3390\/ijms241210296. PMID: 37373443; PMCID: PMC10299688.<\/p>\n<\/li>\n<li class=\"mntl-sources__source\" id=\"citation-2\">\n<p>Mukherjee S, Date A, Patravale V, Korting HC, Roeder A, Weindl G. Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety. Clin Interv Aging. 2006;1(4):327-48. doi: 10.2147\/ciia.2006.1.4.327. PMID: 18046911; PMCID: PMC2699641.<\/p>\n<\/li>\n<li class=\"mntl-sources__source\" id=\"citation-3\">\n<p>Li WH, Wong HK, Serrano J, Randhawa M, Kaur S, Southall MD, Parsa R. Topical stabilized retinol treatment induces the expression of HAS genes and HA production in human skin in vitro and in vivo. Arch Dermatol Res. 2017 May;309(4):275-283. doi: 10.1007\/s00403-017-1723-6. Epub 2017 Feb 28. PMID: 28247017.<\/p>\n<\/li>\n<\/ol>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"loc article-post-content\">\n<div id=\"beauty-breadcrumbs--chips_1-0\" class=\"comp beauty-breadcrumbs--chips mntl-universal-breadcrumbs--chips mntl-block\">\n<div id=\"mntl-breadcrumbs__read-more_1-0\" class=\"comp mntl-breadcrumbs__read-more mntl-text-block text-title-100\">Read more:<\/div>\n<ul id=\"mntl-universal-breadcrumbs_1-0\" class=\"comp mntl-universal-breadcrumbs mntl-block text-label-300 breadcrumbs\" data-tracking-container=\"true\">\n<li id=\"mntl-breadcrumbs__item_1-0\" class=\"comp mntl-breadcrumbs__item mntl-block\"><span class=\"link__wrapper\">Skin<\/span><\/li>\n<li id=\"mntl-breadcrumbs__item_2-0\" class=\"comp mntl-breadcrumbs__item mntl-block\"><span class=\"link__wrapper\">Face Care<\/span><\/li>\n<\/ul>\n<\/div>\n<\/div>\n<\/article>\n<div class=\"loc article-content\">\n<div id=\"article__broad-video-jw_1-0\" class=\"comp article__broad-video-jw mntl-jwplayer-broad mntl-block is-hidden\" data-pixel-depth=\"100\">\n<div id=\"mntl-jwplayer-broad__title_1-0\" class=\"comp mntl-jwplayer-broad__title mntl-block\"><button id=\"mntl-jwplayer-broad__title-icon--close_1-0\" class=\"comp mntl-jwplayer-broad__title-icon--close mntl-block text-label-100\" data-click-tracked=\"false\"><span id=\"mntl-text-block_2-0\" class=\"comp mntl-text-block\">Close<\/span><\/button><\/div>\n<\/div>\n<div id=\"mntl-block_2-0\" class=\"comp mntl-block article__body right-rail\">\n<figure id=\"mntl-universal-primary-image_1-0\" class=\"comp mntl-universal-primary-image primary-image\" data-tracking-container=\"true\">\n<div class=\"primary-image__media\">\n<div class=\"img-placeholder\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/analyse.optim.biz\/wp-content\/uploads\/2026\/02\/skincare-2-a9b87ad2a2b142379b8bf91d791cc5d1-4.webp\" width=\"1280\" height=\"960\" alt=\"A closeup of an open skincare tube with product visible at the top\" class=\" primary-image__image mntl-primary-image--blurry\" title=\"skincare-2-a9b87ad2a2b142379b8bf91d791cc5d1-4\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/analyse.optim.biz\/wp-content\/uploads\/2026\/02\/skincare-2-a9b87ad2a2b142379b8bf91d791cc5d1-4.webp\" width=\"1280\" height=\"960\" class=\"loaded primary-img--noscript primary-image__image mntl-primary-image--blurry\" alt=\"A closeup of an open skincare tube with product visible at the top\" title=\"skincare-2-a9b87ad2a2b142379b8bf91d791cc5d1-4\"><\/div>\n<\/div><figcaption id=\"primary-image__figcap_1-0\" class=\"comp primary-image__figcap mntl-figure-caption figure-article-caption\"><span class=\"figure-article-caption-owner\"><\/p>\n<p>Death to Stock<\/p>\n<p><\/span><\/figcaption><\/figure>\n<div id=\"mntl-sc-page_1-0\" class=\"comp mntl-sc-page mntl-block\" data-sc-sticky-offset=\"125\" data-sc-ad-label-height=\"16\" data-sc-ad-track-spacing=\"100\" data-sc-min-track-height=\"250\" data-sc-max-track-height=\"600\" data-sc-breakpoint=\"50em\" data-sc-load-immediate=\"5\" data-sc-content-positions=\"[1, 1250, 1, 1, 1, 1, 1, 1, 1]\" data-bind-scroll-on-start=\"true\">\n<div id=\"mntl-sc-block_1-0\" class=\"comp mntl-sc-block beauty-sc-block-callout--finalverdict beauty-sc-block-callout mntl-sc-block-callout mntl-block theme-finalverdict\" data-tracking-id=\"mntl-sc-block-callout\" data-tracking-container=\"true\">\n<p id=\"mntl-sc-block-callout-heading_1-0\" class=\"comp mntl-sc-block-callout-heading mntl-text-block\">Key Takeaways<\/p>\n<div id=\"mntl-sc-block-callout-body_1-0\" class=\"comp mntl-sc-block-callout-body mntl-text-block\">\n<ul>\n<li>Hyaluronic acid and retinol can be used together to enhance your skincare routine without causing irritation. <\/li>\n<li>Hyaluronic acid helps mitigate retinol&#8217;s drying effects by increasing skin hydration and improving ingredient absorption. <\/li>\n<li>Apply retinol first, then follow with a hyaluronic acid serum and moisturizer to lock in hydration effectively.<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<p id=\"mntl-sc-block_2-0\" class=\"comp mntl-sc-block beauty-sc-block-html mntl-sc-block-html\"> Hyaluronic acid is a hydrating hero, and retinol is the anti-aging, anti-acne powerhouse, so between the two of them, you&#8217;ve got pretty much everything you need, right? Not so fast&#8230;first, it&#8217;s important to know whether the two can even be paired together.\n<\/p>\n<p id=\"mntl-sc-block_4-0\" class=\"comp mntl-sc-block beauty-sc-block-html mntl-sc-block-html\"> While many of us obsess over the basics\u2014the cleansing, moisturizing, and protecting of the skin\u2014determining how the ingredients you\u2019re using interact is equally as important. To help, we went to board-certified dermatologists Jeremy Fenton, MD, and Ivy DeRosa, MD. Below, they share their expert insights into how hyaluronic acid and retinol work (or don&#8217;t) as a pair.<strong> Keep reading to learn more.<\/strong><\/p>\n<div id=\"mntl-sc-block_6-0\" class=\"comp mntl-sc-block beauty-sc-block-callout--meetourexpert beauty-sc-block-callout mntl-sc-block-callout mntl-block theme-meetourexpert\" data-tracking-id=\"mntl-sc-block-callout\" data-tracking-container=\"true\">\n<p id=\"mntl-sc-block-callout-heading_2-0\" class=\"comp mntl-sc-block-callout-heading mntl-text-block\">Meet the Experts<\/p>\n<div id=\"mntl-sc-block-callout-body_2-0\" class=\"comp mntl-sc-block-callout-body mntl-text-block\">\n<ul>\n<li>\u200b\u200bJeremy Fenton, MD, is a board-certified dermatologist at Schweiger Dermatology Group in New York City.<\/li>\n<li>Ivy DeRosa, MD, is a board-certified medical and cosmetic dermatologist with a small private practice outside of Philadelphia.<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<h2 id=\"mntl-sc-block_7-0\" class=\"comp mntl-sc-block beauty-sc-block-heading mntl-sc-block-heading\"><span class=\"mntl-sc-block-heading__text text-title-300\"> What Is Hyaluronic Acid? <\/span><\/h2>\n<p id=\"mntl-sc-block_8-0\" class=\"comp mntl-sc-block beauty-sc-block-html mntl-sc-block-html\"> Hyaluronic acid is a hydrating ingredient that moisturizes skin, reduces the appearance of wrinkles, replenishes cell moisture, and speeds wound healing. To get more scientific about it, as Dr. DeRosa explains, &#8220;Hyaluronic acid (HA) is a molecule in a class called humectants. Their job is to help retain water in your skin.&#8221; And, as we know, hydration gives skin that dewy, glowy effect we all strive for.\n<\/p>\n<p id=\"mntl-sc-block_10-0\" class=\"comp mntl-sc-block beauty-sc-block-html mntl-sc-block-html\"> Hyaluronic acid &#8220;comes in many different forms over the counter, like serums or lotions, and help to fill the nooks and crannies our skin develops over time due to pollution, sun damage, and the normal aging process,&#8221; Dr. DeRosa says, adding: &#8220;HAs don&#8217;t change the architecture of your skin in the long run, as retinoids do, but they can help for a temporary improvement in the look and feel of your skin.&#8221;\n<\/p>\n<p id=\"mntl-sc-block_12-0\" class=\"comp mntl-sc-block beauty-sc-block-html mntl-sc-block-html\"> It\u2019s generally safe for all skin types and has no known side effects (at least when applied topically).\n<\/p>\n<h2 id=\"mntl-sc-block_14-0\" class=\"comp mntl-sc-block beauty-sc-block-heading mntl-sc-block-heading\"><span class=\"mntl-sc-block-heading__text text-title-300\"> What Is Retinol? <\/span><\/h2>\n<p id=\"mntl-sc-block_15-0\" class=\"comp mntl-sc-block beauty-sc-block-html mntl-sc-block-html\"> If hyaluronic acid is the popular girl who\u2019s nice to everyone, think of retinol as her equally popular but very intimidating best friend. According to Dr. Fenton, retinol is an antioxidant that increases cell turnover, boosts collagen production, and regulates oil production\u2014it\u2019s regularly lauded as a godsend for anyone looking to address texture, acne, or signs of aging. It can also work synergistically with other topicals. &#8220;Retinol may be helpful in combination with other topical treatments because it exfoliates the skin and can allow ingredients to penetrate deeper, making them more effective,&#8221; says Dr. Fenton.\n<\/p>\n<p id=\"mntl-sc-block_17-0\" class=\"comp mntl-sc-block beauty-sc-block-html mntl-sc-block-html\"> But retinol also comes with some serious side effects (both doctors note dryness, peeling, and irritation) and the potential for intense, prolonged purging. Hence the intimidation.\n<\/p>\n<h2 id=\"mntl-sc-block_19-0\" class=\"comp mntl-sc-block beauty-sc-block-heading mntl-sc-block-heading\"><span class=\"mntl-sc-block-heading__text text-title-300\"> Can You Use Hyaluronic Acid and Retinol Together? <\/span><\/h2>\n<p id=\"mntl-sc-block_20-0\" class=\"comp mntl-sc-block beauty-sc-block-html mntl-sc-block-html\"> Much like the girls in our high school analogy, hyaluronic acid and retinol are a match made in heaven. Where retinol is rough, hyaluronic acid is soft; where hyaluronic acid is weak, retinol is strong. Together, they balance each other out without compromising the things that make them unique. It\u2019s exactly what makes the combination one of the most popular across all skincare ingredients.<\/p>\n<div id=\"mntl-sc-block_22-0\" class=\"comp mntl-sc-block beauty-sc-block-callout--tips beauty-sc-block-callout mntl-sc-block-callout mntl-block theme-tips\" data-tracking-id=\"mntl-sc-block-callout\" data-tracking-container=\"true\">\n<p id=\"mntl-sc-block-callout-heading_3-0\" class=\"comp mntl-sc-block-callout-heading mntl-text-block\">Key Takeaways<\/p>\n<div id=\"mntl-sc-block-callout-body_3-0\" class=\"comp mntl-sc-block-callout-body mntl-text-block\">\n<ul>\n<li>Hyaluronic acid and retinol can be used within the same routine without concern for irritation.<\/li>\n<li>Due to its powerful hydrating properties, hyaluronic acid can even help mitigate the side effects of retinol.<\/li>\n<li>When using both ingredients together, apply your retinol first, then follow up with a hyaluronic acid serum.<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<h2 id=\"mntl-sc-block_23-0\" class=\"comp mntl-sc-block beauty-sc-block-heading mntl-sc-block-heading\"><span class=\"mntl-sc-block-heading__text text-title-300\"> Benefits of Using Hyaluronic Acid and Retinol Together <\/span><\/h2>\n<p id=\"mntl-sc-block_24-0\" class=\"comp mntl-sc-block beauty-sc-block-html mntl-sc-block-html\"> As we said, hyaluronic acid and retinol are the ultimate duo. Together, they have a sort of synergistic effect, making it easier to reap the benefits of retinol without suffering any of the usual dryness thanks to the moisture boost from hyaluronic acid.\u00a0\n<\/p>\n<p id=\"mntl-sc-block_26-0\" class=\"comp mntl-sc-block beauty-sc-block-html mntl-sc-block-html\"> Hyaluronic acid helps keep retinol in check, increasing the permeability of the skin. So when combined, the two ingredients can leave your skin clearer, smoother, and more hydrated and moisturized. What more could you ask for?\n<\/p>\n<p id=\"mntl-sc-block_28-0\" class=\"comp mntl-sc-block beauty-sc-block-html mntl-sc-block-html\"> Not to mention it\u2019s a combination you might already be using: many moisturizers contain hyaluronic acid anyway. Likewise, Dr. DeRosa says many high-quality, over-the-counter retinol products are formulated with hydrating and calming ingredients to help mitigate irritation, so there\u2019s a chance your retinol even contains some hyaluronic acid anyway.\n<\/p>\n<h2 id=\"mntl-sc-block_30-0\" class=\"comp mntl-sc-block beauty-sc-block-heading mntl-sc-block-heading\"><span class=\"mntl-sc-block-heading__text text-title-300\"> Potential Side Effects of Using Hyaluronic Acid with Retinol <\/span><\/h2>\n<p id=\"mntl-sc-block_31-0\" class=\"comp mntl-sc-block beauty-sc-block-html mntl-sc-block-html\"> As is the case with all skincare ingredients, there\u2019s always some sort of potential for irritation. That potential is fairly high with retinol and very low with hyaluronic acid.\u00a0So, yes, there is still a chance of irritation but it is a very, very small one\u2014and that irritation would likely be caused not by the <em>combination<\/em> of retinol and hyaluronic acid but by the retinol itself.\n<\/p>\n<h2 id=\"mntl-sc-block_33-0\" class=\"comp mntl-sc-block beauty-sc-block-heading mntl-sc-block-heading\"><span class=\"mntl-sc-block-heading__text text-title-300\"> How to Use Hyaluronic Acid With Retinol <\/span><\/h2>\n<p id=\"mntl-sc-block_34-0\" class=\"comp mntl-sc-block beauty-sc-block-html mntl-sc-block-html\"> Dr. DeRosa provides the following timeline for the application of HA and retinol products: &#8220;If dealing with sensitive or dry skin, a great way to tolerate a retinol is by first cleansing with a gentle wash; no scrubs, toners or physical exfoliants. Then apply a pea-sized amount (that&#8217;s right- just a pea, more is not better) of retinol to the face, and apply a small amount of a hyaluronic acid serum followed by a moisturizer cream. The moisturizer helps to lock in the HA so it can amplify the helpfulness of your moisturizer.&#8221;\n<\/p>\n<p id=\"mntl-sc-block_36-0\" class=\"comp mntl-sc-block beauty-sc-block-html mntl-sc-block-html\"> Try applying a moisturizer or hyaluronic acid in gel form around 30 minutes after applying retinol so that the treatment can dry and soak into the skin before moisturizing. For those with dry or sensitive skin, try using a hyaluronic acid serum prior to retinol. Then, once the retinol has dried, apply a moisturizer.\n<\/p>\n<h2 id=\"mntl-sc-block_38-0\" class=\"comp mntl-sc-block beauty-sc-block-heading mntl-sc-block-heading\"><span class=\"mntl-sc-block-heading__text text-title-300\"> How to Minimize Irritation <\/span><\/h2>\n<p id=\"mntl-sc-block_39-0\" class=\"comp mntl-sc-block beauty-sc-block-html mntl-sc-block-html\"> An important note: the importance of proper application methods when it comes to retinol and hyaluronic acid cannot be overstates. Be sure to give your retinol time to dry and seep into the skin before moving on to the next steps. This will minimize irritation.\n<\/p>\n<h2 id=\"mntl-sc-block_41-0\" class=\"comp mntl-sc-block beauty-sc-block-heading mntl-sc-block-heading\"><span class=\"mntl-sc-block-heading__text text-title-300\"> The Final Takeaway <\/span><\/h2>\n<p id=\"mntl-sc-block_42-0\" class=\"comp mntl-sc-block beauty-sc-block-html mntl-sc-block-html\"> Not only <em>can<\/em> you use hyaluronic acid and retinol together, but both doctors actually <em>encourage<\/em> you to. And they\u2019re not alone: Few other ingredient combinations are as well-regarded as hyaluronic acid and retinol in the skincare community.\n<\/p>\n<p id=\"mntl-sc-block_44-0\" class=\"comp mntl-sc-block beauty-sc-block-html mntl-sc-block-html\"> On their own, hyaluronic acid and retinol are both considered two of the most popular ingredients in anti-aging skincare products. Because hyaluronic acid draws water into the skin while retinol speeds cellular turnover, you can counteract some of retinol\u2019s notorious drying properties while still allowing the ingredient to penetrate the outer layer of the skin. If anything, results are only better when you combine the two. So give the combo a try\u2014you can thank me later.\n<\/p>\n<\/div>\n<div id=\"citation-sources_1-0\" class=\"comp citation-sources mntl-article-sources mntl-expandable-block u-article-styles\" data-scroll-offset=\"70\">\n<div class=\"loc toggle-content\">\n<div id=\"mntl-article-sources__wrapper_1-0\" class=\"comp mntl-article-sources__wrapper mntl-block\" data-click-tracked=\"true\"><span id=\"mntl-article-sources__heading_1-0\" class=\"comp mntl-article-sources__heading mntl-text-block\">Article Sources<\/span><\/div>\n<\/div>\n<div class=\"loc expandable-content\">\n<div id=\"citation-sources__text_1-0\" class=\"comp citation-sources__text mntl-text-block\">Byrdie takes every opportunity to use high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial guidelines to learn more about how we keep our content accurate, reliable and trustworthy.<\/div>\n<div id=\"mntl-article-sources__citation-sources_1-0\" class=\"comp mntl-article-sources__citation-sources mntl-citation-sources mntl-sources\" data-tracking-container=\"true\">\n<ol class=\"mntl-sources__content\">\n<li class=\"mntl-sources__source\" id=\"citation-1\">\n<p>Iaconisi GN, Lunetti P, Gallo N, Cappello AR, Fiermonte G, Dolce V, Capobianco L. Hyaluronic Acid: A Powerful Biomolecule with Wide-Ranging Applications-A Comprehensive Review. Int J Mol Sci. 2023 Jun 18;24(12):10296. doi: 10.3390\/ijms241210296. PMID: 37373443; PMCID: PMC10299688.<\/p>\n<\/li>\n<li class=\"mntl-sources__source\" id=\"citation-2\">\n<p>Mukherjee S, Date A, Patravale V, Korting HC, Roeder A, Weindl G. Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety. Clin Interv Aging. 2006;1(4):327-48. doi: 10.2147\/ciia.2006.1.4.327. PMID: 18046911; PMCID: PMC2699641.<\/p>\n<\/li>\n<li class=\"mntl-sources__source\" id=\"citation-3\">\n<p>Li WH, Wong HK, Serrano J, Randhawa M, Kaur S, Southall MD, Parsa R. Topical stabilized retinol treatment induces the expression of HAS genes and HA production in human skin in vitro and in vivo. Arch Dermatol Res. 2017 May;309(4):275-283. doi: 10.1007\/s00403-017-1723-6. Epub 2017 Feb 28. PMID: 28247017.<\/p>\n<\/li>\n<\/ol>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div id=\"mntl-sc-page_1-0\" class=\"comp mntl-sc-page mntl-block\" data-sc-sticky-offset=\"125\" data-sc-ad-label-height=\"16\" data-sc-ad-track-spacing=\"100\" data-sc-min-track-height=\"250\" data-sc-max-track-height=\"600\" data-sc-breakpoint=\"50em\" data-sc-load-immediate=\"5\" data-sc-content-positions=\"[1, 1250, 1, 1, 1, 1, 1, 1, 1]\" data-bind-scroll-on-start=\"true\">\n<div id=\"mntl-sc-block_1-0\" class=\"comp mntl-sc-block beauty-sc-block-callout--finalverdict beauty-sc-block-callout mntl-sc-block-callout mntl-block theme-finalverdict\" data-tracking-id=\"mntl-sc-block-callout\" data-tracking-container=\"true\">\n<p id=\"mntl-sc-block-callout-heading_1-0\" class=\"comp mntl-sc-block-callout-heading mntl-text-block\">Key Takeaways<\/p>\n<div id=\"mntl-sc-block-callout-body_1-0\" class=\"comp mntl-sc-block-callout-body mntl-text-block\">\n<ul>\n<li>Hyaluronic acid and retinol can be used together to enhance your skincare routine without causing irritation. <\/li>\n<li>Hyaluronic acid helps mitigate retinol&#8217;s drying effects by increasing skin hydration and improving ingredient absorption. <\/li>\n<li>Apply retinol first, then follow with a hyaluronic acid serum and moisturizer to lock in hydration effectively.<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<p id=\"mntl-sc-block_2-0\" class=\"comp mntl-sc-block beauty-sc-block-html mntl-sc-block-html\"> Hyaluronic acid is a hydrating hero, and retinol is the anti-aging, anti-acne powerhouse, so between the two of them, you&#8217;ve got pretty much everything you need, right? Not so fast&#8230;first, it&#8217;s important to know whether the two can even be paired together.\n<\/p>\n<p id=\"mntl-sc-block_4-0\" class=\"comp mntl-sc-block beauty-sc-block-html mntl-sc-block-html\"> While many of us obsess over the basics\u2014the cleansing, moisturizing, and protecting of the skin\u2014determining how the ingredients you\u2019re using interact is equally as important. To help, we went to board-certified dermatologists Jeremy Fenton, MD, and Ivy DeRosa, MD. Below, they share their expert insights into how hyaluronic acid and retinol work (or don&#8217;t) as a pair.<strong> Keep reading to learn more.<\/strong><\/p>\n<div id=\"mntl-sc-block_6-0\" class=\"comp mntl-sc-block beauty-sc-block-callout--meetourexpert beauty-sc-block-callout mntl-sc-block-callout mntl-block theme-meetourexpert\" data-tracking-id=\"mntl-sc-block-callout\" data-tracking-container=\"true\">\n<p id=\"mntl-sc-block-callout-heading_2-0\" class=\"comp mntl-sc-block-callout-heading mntl-text-block\">Meet the Experts<\/p>\n<div id=\"mntl-sc-block-callout-body_2-0\" class=\"comp mntl-sc-block-callout-body mntl-text-block\">\n<ul>\n<li>\u200b\u200bJeremy Fenton, MD, is a board-certified dermatologist at Schweiger Dermatology Group in New York City.<\/li>\n<li>Ivy DeRosa, MD, is a board-certified medical and cosmetic dermatologist with a small private practice outside of Philadelphia.<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<h2 id=\"mntl-sc-block_7-0\" class=\"comp mntl-sc-block beauty-sc-block-heading mntl-sc-block-heading\"><span class=\"mntl-sc-block-heading__text text-title-300\"> What Is Hyaluronic Acid? <\/span><\/h2>\n<p id=\"mntl-sc-block_8-0\" class=\"comp mntl-sc-block beauty-sc-block-html mntl-sc-block-html\"> Hyaluronic acid is a hydrating ingredient that moisturizes skin, reduces the appearance of wrinkles, replenishes cell moisture, and speeds wound healing. To get more scientific about it, as Dr. DeRosa explains, &#8220;Hyaluronic acid (HA) is a molecule in a class called humectants. Their job is to help retain water in your skin.&#8221; And, as we know, hydration gives skin that dewy, glowy effect we all strive for.\n<\/p>\n<p id=\"mntl-sc-block_10-0\" class=\"comp mntl-sc-block beauty-sc-block-html mntl-sc-block-html\"> Hyaluronic acid &#8220;comes in many different forms over the counter, like serums or lotions, and help to fill the nooks and crannies our skin develops over time due to pollution, sun damage, and the normal aging process,&#8221; Dr. DeRosa says, adding: &#8220;HAs don&#8217;t change the architecture of your skin in the long run, as retinoids do, but they can help for a temporary improvement in the look and feel of your skin.&#8221;\n<\/p>\n<p id=\"mntl-sc-block_12-0\" class=\"comp mntl-sc-block beauty-sc-block-html mntl-sc-block-html\"> It\u2019s generally safe for all skin types and has no known side effects (at least when applied topically).\n<\/p>\n<h2 id=\"mntl-sc-block_14-0\" class=\"comp mntl-sc-block beauty-sc-block-heading mntl-sc-block-heading\"><span class=\"mntl-sc-block-heading__text text-title-300\"> What Is Retinol? <\/span><\/h2>\n<p id=\"mntl-sc-block_15-0\" class=\"comp mntl-sc-block beauty-sc-block-html mntl-sc-block-html\"> If hyaluronic acid is the popular girl who\u2019s nice to everyone, think of retinol as her equally popular but very intimidating best friend. According to Dr. Fenton, retinol is an antioxidant that increases cell turnover, boosts collagen production, and regulates oil production\u2014it\u2019s regularly lauded as a godsend for anyone looking to address texture, acne, or signs of aging. It can also work synergistically with other topicals. &#8220;Retinol may be helpful in combination with other topical treatments because it exfoliates the skin and can allow ingredients to penetrate deeper, making them more effective,&#8221; says Dr. Fenton.\n<\/p>\n<p id=\"mntl-sc-block_17-0\" class=\"comp mntl-sc-block beauty-sc-block-html mntl-sc-block-html\"> But retinol also comes with some serious side effects (both doctors note dryness, peeling, and irritation) and the potential for intense, prolonged purging. Hence the intimidation.\n<\/p>\n<h2 id=\"mntl-sc-block_19-0\" class=\"comp mntl-sc-block beauty-sc-block-heading mntl-sc-block-heading\"><span class=\"mntl-sc-block-heading__text text-title-300\"> Can You Use Hyaluronic Acid and Retinol Together? <\/span><\/h2>\n<p id=\"mntl-sc-block_20-0\" class=\"comp mntl-sc-block beauty-sc-block-html mntl-sc-block-html\"> Much like the girls in our high school analogy, hyaluronic acid and retinol are a match made in heaven. Where retinol is rough, hyaluronic acid is soft; where hyaluronic acid is weak, retinol is strong. Together, they balance each other out without compromising the things that make them unique. It\u2019s exactly what makes the combination one of the most popular across all skincare ingredients.<\/p>\n<div id=\"mntl-sc-block_22-0\" class=\"comp mntl-sc-block beauty-sc-block-callout--tips beauty-sc-block-callout mntl-sc-block-callout mntl-block theme-tips\" data-tracking-id=\"mntl-sc-block-callout\" data-tracking-container=\"true\">\n<p id=\"mntl-sc-block-callout-heading_3-0\" class=\"comp mntl-sc-block-callout-heading mntl-text-block\">Key Takeaways<\/p>\n<div id=\"mntl-sc-block-callout-body_3-0\" class=\"comp mntl-sc-block-callout-body mntl-text-block\">\n<ul>\n<li>Hyaluronic acid and retinol can be used within the same routine without concern for irritation.<\/li>\n<li>Due to its powerful hydrating properties, hyaluronic acid can even help mitigate the side effects of retinol.<\/li>\n<li>When using both ingredients together, apply your retinol first, then follow up with a hyaluronic acid serum.<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<h2 id=\"mntl-sc-block_23-0\" class=\"comp mntl-sc-block beauty-sc-block-heading mntl-sc-block-heading\"><span class=\"mntl-sc-block-heading__text text-title-300\"> Benefits of Using Hyaluronic Acid and Retinol Together <\/span><\/h2>\n<p id=\"mntl-sc-block_24-0\" class=\"comp mntl-sc-block beauty-sc-block-html mntl-sc-block-html\"> As we said, hyaluronic acid and retinol are the ultimate duo. Together, they have a sort of synergistic effect, making it easier to reap the benefits of retinol without suffering any of the usual dryness thanks to the moisture boost from hyaluronic acid.\u00a0\n<\/p>\n<p id=\"mntl-sc-block_26-0\" class=\"comp mntl-sc-block beauty-sc-block-html mntl-sc-block-html\"> Hyaluronic acid helps keep retinol in check, increasing the permeability of the skin. So when combined, the two ingredients can leave your skin clearer, smoother, and more hydrated and moisturized. What more could you ask for?\n<\/p>\n<p id=\"mntl-sc-block_28-0\" class=\"comp mntl-sc-block beauty-sc-block-html mntl-sc-block-html\"> Not to mention it\u2019s a combination you might already be using: many moisturizers contain hyaluronic acid anyway. Likewise, Dr. DeRosa says many high-quality, over-the-counter retinol products are formulated with hydrating and calming ingredients to help mitigate irritation, so there\u2019s a chance your retinol even contains some hyaluronic acid anyway.\n<\/p>\n<h2 id=\"mntl-sc-block_30-0\" class=\"comp mntl-sc-block beauty-sc-block-heading mntl-sc-block-heading\"><span class=\"mntl-sc-block-heading__text text-title-300\"> Potential Side Effects of Using Hyaluronic Acid with Retinol <\/span><\/h2>\n<p id=\"mntl-sc-block_31-0\" class=\"comp mntl-sc-block beauty-sc-block-html mntl-sc-block-html\"> As is the case with all skincare ingredients, there\u2019s always some sort of potential for irritation. That potential is fairly high with retinol and very low with hyaluronic acid.\u00a0So, yes, there is still a chance of irritation but it is a very, very small one\u2014and that irritation would likely be caused not by the <em>combination<\/em> of retinol and hyaluronic acid but by the retinol itself.\n<\/p>\n<h2 id=\"mntl-sc-block_33-0\" class=\"comp mntl-sc-block beauty-sc-block-heading mntl-sc-block-heading\"><span class=\"mntl-sc-block-heading__text text-title-300\"> How to Use Hyaluronic Acid With Retinol <\/span><\/h2>\n<p id=\"mntl-sc-block_34-0\" class=\"comp mntl-sc-block beauty-sc-block-html mntl-sc-block-html\"> Dr. DeRosa provides the following timeline for the application of HA and retinol products: &#8220;If dealing with sensitive or dry skin, a great way to tolerate a retinol is by first cleansing with a gentle wash; no scrubs, toners or physical exfoliants. Then apply a pea-sized amount (that&#8217;s right- just a pea, more is not better) of retinol to the face, and apply a small amount of a hyaluronic acid serum followed by a moisturizer cream. The moisturizer helps to lock in the HA so it can amplify the helpfulness of your moisturizer.&#8221;\n<\/p>\n<p id=\"mntl-sc-block_36-0\" class=\"comp mntl-sc-block beauty-sc-block-html mntl-sc-block-html\"> Try applying a moisturizer or hyaluronic acid in gel form around 30 minutes after applying retinol so that the treatment can dry and soak into the skin before moisturizing. For those with dry or sensitive skin, try using a hyaluronic acid serum prior to retinol. Then, once the retinol has dried, apply a moisturizer.\n<\/p>\n<h2 id=\"mntl-sc-block_38-0\" class=\"comp mntl-sc-block beauty-sc-block-heading mntl-sc-block-heading\"><span class=\"mntl-sc-block-heading__text text-title-300\"> How to Minimize Irritation <\/span><\/h2>\n<p id=\"mntl-sc-block_39-0\" class=\"comp mntl-sc-block beauty-sc-block-html mntl-sc-block-html\"> An important note: the importance of proper application methods when it comes to retinol and hyaluronic acid cannot be overstates. Be sure to give your retinol time to dry and seep into the skin before moving on to the next steps. This will minimize irritation.\n<\/p>\n<h2 id=\"mntl-sc-block_41-0\" class=\"comp mntl-sc-block beauty-sc-block-heading mntl-sc-block-heading\"><span class=\"mntl-sc-block-heading__text text-title-300\"> The Final Takeaway <\/span><\/h2>\n<p id=\"mntl-sc-block_42-0\" class=\"comp mntl-sc-block beauty-sc-block-html mntl-sc-block-html\"> Not only <em>can<\/em> you use hyaluronic acid and retinol together, but both doctors actually <em>encourage<\/em> you to. And they\u2019re not alone: Few other ingredient combinations are as well-regarded as hyaluronic acid and retinol in the skincare community.\n<\/p>\n<p id=\"mntl-sc-block_44-0\" class=\"comp mntl-sc-block beauty-sc-block-html mntl-sc-block-html\"> On their own, hyaluronic acid and retinol are both considered two of the most popular ingredients in anti-aging skincare products. Because hyaluronic acid draws water into the skin while retinol speeds cellular turnover, you can counteract some of retinol\u2019s notorious drying properties while still allowing the ingredient to penetrate the outer layer of the skin. If anything, results are only better when you combine the two. So give the combo a try\u2014you can thank me later.\n<\/p>\n<\/div>\n<p> Source URL: https:\/\/www.byrdie.com\/can-you-mix-hyaluronic-acid-and-retinol-11887999<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Is It Safe to Use Hyaluronic Acid With Retinol? Dermatologists Weigh In Hint: You&#8217;re probably already mixing them. By Dani Hardman Dani Hardman Dani is New York-based beauty writer and editor. Her work has been featured in Allure, Elle, InStyle, Well + Good, and more. Byrdie&#8217;s Editorial Guidelines Published on January 19, 2026 08:15AM Reviewed [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":1700907,"comment_status":"open","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2],"tags":[83,226],"class_list":["post-1700905","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-politics","tag-byrdie-com","tag-crawlmanager"],"_links":{"self":[{"href":"https:\/\/analyse.optim.biz\/index.php?rest_route=\/wp\/v2\/posts\/1700905","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/analyse.optim.biz\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/analyse.optim.biz\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/analyse.optim.biz\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/analyse.optim.biz\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1700905"}],"version-history":[{"count":0,"href":"https:\/\/analyse.optim.biz\/index.php?rest_route=\/wp\/v2\/posts\/1700905\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/analyse.optim.biz\/index.php?rest_route=\/wp\/v2\/media\/1700907"}],"wp:attachment":[{"href":"https:\/\/analyse.optim.biz\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1700905"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/analyse.optim.biz\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=1700905"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/analyse.optim.biz\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=1700905"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}