Cinco de Mayo got spicy between Republicans and Democrats … and not in a margarita-on-the-rocks kinda way.

The official White House account on X fired the first shot Tuesday morning … and it wasn’t a tequila shot.

They came right out of the gates with a celebratory Cinco de Mayo message accompanied by an A.I.-generated image of two of the Democratic Party’s top dogs: Hakeem Jeffries, the highest-ranking Democrat in the House, and Chuck Schumer, who leads Democrats in the Senate.

There was nothing borderline about the political message — it shows Jeffries and Schumer in sombreros, sipping margaritas near a U.S. border crossing … with a sign reading “I love illegal immigrants,” a clear jab at Democratic immigration policies that Republicans have hammered for years.

Schumer didn’t take this jab lying down … quickly clapping back at the White House account.

He fired back with a quote post that flipped the script — “Happy Cinco de Mayo, @WhiteHouse!” — and attached a photo of President DonaldTrumpstanding next to Jeffrey Epstein… both wearing sombreros. Message received … and returned with interest.

The back-and-forth didn’t stay light for long … the exchange quickly turned into a partisan pile-on with Democrats and Republicans butting heads in the replies.